Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNbeta. (Q40245065)

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28 December 2019

title

Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNbeta (English)

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Maria Carmen Puertas

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R Pujol-Borrell

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Marta Vives-Pi

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Raquel Planas

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Joan Verdaguer Autonell

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author name string

A Alba

2

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R Ampudia

5

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X Pastor

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H Okamoto

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S Takasawa

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W Gurr

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publication date

10 August 2006

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28 December 2019

volume

49

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28 December 2019

issue

10

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28 December 2019

page(s)

2379-2387

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https://scigraph.springernature.com/pub.10.1007/s00125-006-0365-6

28 December 2019

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0 references

cites work

IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

1 reference

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Reg gene family and human diseases

21 January 2018

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Interleukin-8 regulates expression of Reg protein in Helicobacter pylori-infected gastric mucosa

21 January 2018

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12 December 2020

A novel gene activated in regenerating islets

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12 December 2020

Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice

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12 December 2020

Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer

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12 December 2020

Differentially expressed proteins in the pancreas of diet-induced diabetic mice

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12 December 2020

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

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12 December 2020

Immunostimulation circumvents diabetes in NOD/Lt mice

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12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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12 December 2020

Low dose poly I:C prevents diabetes in the diabetes prone BB rat

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12 December 2020

Diabetes: epidemiology suggests a viral connection

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12 December 2020

Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus

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12 December 2020

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

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12 December 2020

Interferon-beta 1b treatment decreases tumor necrosis factor-alpha and increases interleukin-6 production in multiple sclerosis

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12 December 2020

Type I interferons (alpha/beta) in immunity and autoimmunity

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12 December 2020

Coxsackie B, mumps, rubella, and cytomegalovirus specific IgM responses in patients with juvenile-onset insulin-dependent diabetes mellitus in Britain, Austria, and Australia

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12 December 2020

A new look at viruses in type 1 diabetes.

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12 December 2020

Increased expression of HIP/PAP and regenerating gene III in human inflammatory bowel disease and a murine bacterial reconstitution model.

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12 December 2020

The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells

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12 December 2020

How viral infections affect the autoimmune process leading to type 1 diabetes

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12 December 2020

Engraftment of islets obtained by collagenase and Liberase in diabetic rats: a comparative study

1 reference

12 December 2020

Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy

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12 December 2020

Interferon expression in the pancreases of patients with type I diabetes

1 reference

12 December 2020

Amelioration of Diabetes Mellitus in Partially Depancreatized Rats by Poly(ADP-ribose) Synthetase Inhibitors: Evidence of Islet B-Cell Regeneration

1 reference

12 December 2020

Islet abnormalities associated with an early influx of dendritic cells and macrophages in NOD and NODscid mice

1 reference

12 December 2020

Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1beta and interleukin-6

1 reference

12 December 2020

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

1 reference

12 December 2020

Islet inflammation and hyperplasia induced by the pancreatic islet-specific overexpression of interleukin-6 in transgenic mice.

1 reference

12 December 2020

Evidence for IL-6 production by and effects on the pancreatic beta-cell

1 reference

12 December 2020

The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency

1 reference

12 December 2020

NIT-1, a Pancreatic β-Cell Line Established From a Transgenic NOD/Lt Mouse

1 reference

12 December 2020

Autoantibodies to REG, a beta-cell regeneration factor, in diabetic patients

1 reference

12 December 2020

Progression to islet destruction in a cyclophosphamide-induced transgenic model: a microarray overview

1 reference

12 December 2020

Expression of glutamic acid decarboxylase (GAD) in the α, β and δ cells of normal and diabetic pancreas: implications for the pathogenesis of type I diabetes

1 reference

12 December 2020

B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice.

1 reference

12 December 2020

Evidence from Transgenic Mice That Interferon-β May Be Involved in the Onset of Diabetes Mellitus

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12 December 2020

Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein

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12 December 2020

A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice

1 reference

12 December 2020

Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice

1 reference

12 December 2020

Tolerance to islet autoantigens in type 1 diabetes

1 reference

12 December 2020

Expression of reg protein in rat regenerating islets and its co-localization with insulin in the beta cell secretory granules

1 reference

12 December 2020

Direct evidence that interferon-beta mediates enhanced HLA-class I expression in measles virus-infected cells.

1 reference

12 December 2020

Amelioration of diabetes in nonobese diabetic mice with advanced disease by linomide-induced immunoregulation combined with Reg protein treatment

1 reference

12 December 2020

The NOD mouse: a model of immune dysregulation

1 reference

12 December 2020