Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231. (Q40257029)

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26 December 2019

title

Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231 (English)

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26 December 2019

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4

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26 December 2019

Stefano Thellung

6

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26 December 2019

author name string

A Corsaro

1

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26 December 2019

D Paludi

2

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26 December 2019

V Villa

3

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26 December 2019

K Chiovitti

5

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26 December 2019

C Russo

7

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D Di Cola

8

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P Ballerini

9

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E Patrone

10

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G Schettini

11

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A Aceto

12

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T Florio

13

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26 December 2019

publication date

1 April 2006

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International Journal of Immunopathology and Pharmacology

26 December 2019

published in

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volume

19

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26 December 2019

issue

2

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26 December 2019

page(s)

339-356

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26 December 2019

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Molecular biology of prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Pathologic conformations of prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Prion diseases: what is the neurotoxic molecule?

21 January 2018

1 reference

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Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein.

21 January 2018

1 reference

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Identification of novel proteinase K-resistant C-terminal fragments of PrP in Creutzfeldt-Jakob disease

21 January 2018

1 reference

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Large-scale production, purification and refolding of the full-length cellular prion protein from Syrian golden hamster in Escherichia coli using the glutathione S-transferase-fusion system

21 January 2018

1 reference

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Multiple folding pathways for heterologously expressed human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Identification of a conserved N-capping box important for the structural autonomy of the prion alpha 3-helix: the disease associated D202N mutation destabilizes the helical conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

1 reference

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p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Neurotoxicity of a prion protein fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

1 reference

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Potent inhibition of scrapie-associated PrP accumulation by congo red

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

A neurotoxic prion protein fragment induces rat astroglial proliferation and hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Aggregation and fibrillization of the recombinant human prion protein huPrP90-231.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

The peculiar nature of unfolding of the human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

The anti-prion activity of Congo red. Putative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

A nonfibrillar form of the fusogenic prion protein fragment [118-135] induces apoptotic cell death in rat cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

On the mechanism of alpha-helix to beta-sheet transition in the recombinant prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Pathway complexity of prion protein assembly into amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Prefibrillar amyloid protein aggregates share common features of cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F039463200601900211

Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic

21 January 2018

1 reference

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10.1177/039463200601900211

21 January 2018

Identifiers

DOI

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26 December 2019

1 reference