The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells (Q40264466)

19 September 2017

The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells (English)

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19 September 2017

Dominique Joly

1

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19 September 2017

Shuta Ishibe

2

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19 September 2017

Christian Nickel

3

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19 September 2017

Zhiheng Yu

4

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19 September 2017

Stefan Somlo

5

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19 September 2017

Lloyd G Cantley

6

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19 September 2017

language of work or name

English

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publication date

21 June 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

36

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19 September 2017

26329-26339

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The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Human disease: calcium signaling in polycystic kidney disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601373200

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601373200

Role of polycystins in renal tubulogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601373200

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601373200

Focal adhesion regulation of cell behavior.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601373200

The polycystic kidney disease 1 gene product modulates Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Polycystin-1 interacts with intermediate filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Anchorage-dependent ERK signaling--mechanisms and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

The HGF/SF-induced phosphorylation of paxillin, matrix adhesion, and invasion of prostate cancer cells were suppressed by NK4, an HGF/SF variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

21 January 2018

Lamellipodia in invasion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

v-Src's hold over actin and cell adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601373200

RhoA and ROCK promote migration by limiting membrane protrusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Layilin, a novel integral membrane protein, is a hyaluronan receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

Mutation analysis of the entire PKD1 gene: genetic and diagnostic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601373200

21 January 2018

Identifiers

DOI

10.1074/JBC.M601373200

1 reference

19 September 2017

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