Role of c-Src in human MCF7 breast cancer cell tumorigenesis (Q40275151)

19 September 2017

Role of c-Src in human MCF7 breast cancer cell tumorigenesis (English)

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19 September 2017

Lorena González

1

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19 September 2017

María Teresa Agulló-Ortuño

2

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19 September 2017

José Manuel García-Martínez

3

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19 September 2017

Annarica Calcabrini

4

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19 September 2017

Carlos Gamallo

5

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19 September 2017

José Palacios

6

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19 September 2017

Ana Aranda

7

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19 September 2017

Jorge Martín-Pérez

8

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19 September 2017

language of work or name

English

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publication date

25 May 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

30

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19 September 2017

20851-20864

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Cellular functions regulated by Src family kinases

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Elevated c-Src is linked to altered cell-matrix adhesion rather than proliferation in KM12C human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

The interplay between Src and integrins in normal and tumor biology

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601570200

Enhanced v-Src-induced oncogenic transformation in the absence of focal adhesion kinase is mediated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Structure and regulation of Src family kinases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M601570200

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

v-Src's hold over actin and cell adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Mitogenic activity of estrogens in human breast cancer cells does not rely on direct induction of mitogen-activated protein kinase/extracellularly regulated kinase or phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Phosphorylation of vinculin by pp60src: What might it mean?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

An essential role for Src kinase in ErbB receptor signaling through the MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

C-myc gene expression alone is sufficient to confer resistance to antiestrogen in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Regulation of the VLA integrin-ligand interactions through the beta 1 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

P-cadherin expression reduced in squamous cell carcinoma of the oral cavity: an indicatior of poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Role of integrins in cell invasion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Src family kinases in tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Differential effect of the focal adhesion kinase Y397F mutant on v-Src-stimulated cell invasion and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Combinatorial target-guided ligand assembly: identification of potent subtype-selective c-Src inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Activating SRC mutation in a subset of advanced human colon cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Prolactin induces c-Myc expression and cell survival through activation of Src/Akt pathway in lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Sex steroid hormones act as growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

TGF-beta1-mediated activations of c-Src and Rac1 modulate levels of cyclins and p27(Kip1) CDK inhibitor in hepatoma cells replated on fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Cleavage of p130Cas in anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

Transmembrane tyrosine phosphatase LAR induces apoptosis by dephosphorylating and destabilizing p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601570200

21 January 2018

Identifiers

DOI

10.1074/JBC.M601570200

1 reference

19 September 2017

1 reference