The mucin Muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3. (Q40281070)

19 September 2017

The mucin Muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3. (English)

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19 September 2017

Melanie Funes

1

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19 September 2017

Jamie K Miller

2

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19 September 2017

Cary Lai

3

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19 September 2017

Kermit L Carraway

4

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19 September 2017

Colleen Sweeney

5

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19 September 2017

language of work or name

English

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publication date

11 May 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

28

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19 September 2017

19310-19319

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Untangling the ErbB signalling network

19 September 2017

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The ErbB receptors and their role in cancer progression.

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Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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Muc4/sialomucin complex, the intramembrane ErbB2 ligand, in cancer and epithelia: to protect and to survive

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Differential localization of ErbB2 in different tissues of the rat female reproductive tract: implications for the use of specific antibodies for ErbB2 analysis

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An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling

21 January 2018

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Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor

21 January 2018

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Presence of MUC4 in human milk and at the luminal surfaces of blood vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603225200

Reversible disruption of cell-matrix and cell-cell interactions by overexpression of sialomucin complex

21 January 2018

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Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors

21 January 2018

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An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels

21 January 2018

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The transforming potential of the c-erbB-2 protein is regulated by its autophosphorylation at the carboxyl-terminal domain

21 January 2018

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Phosphorylation of tyrosine 1248-ERBB2 measured by chemiluminescence-linked immunoassay is an independent predictor of poor prognosis in primary breast cancer patients.

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Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase

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Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor

21 January 2018

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Ligand stimulation reduces platelet-derived growth factor beta-receptor susceptibility to tyrosine dephosphorylation

21 January 2018

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Adhesion proteins in the biology of breast cancer: contribution of CD44.

21 January 2018

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Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

21 January 2018

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CD44 enhances neuregulin signaling by Schwann cells

21 January 2018

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The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling

21 January 2018

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Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways

21 January 2018

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Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

21 January 2018

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Trafficking of the ErbB receptors and its influence on signaling

21 January 2018

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The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

21 January 2018

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Deregulated Akt3 activity promotes development of malignant melanoma

21 January 2018

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

21 January 2018

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Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis.

21 January 2018

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Diagnostic value of MUC4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma.

21 January 2018

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MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type

21 January 2018

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Sialomucin expression is associated with erbB-2 oncoprotein overexpression, early recurrence, and cancer death in non-small-cell lung cancer

21 January 2018

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The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

21 January 2018

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Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

21 January 2018

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MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met

21 January 2018

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An ErbB2-Muc4 complex in rat ocular surface epithelia

21 January 2018

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Potentiation of metastasis by cell surface sialomucin complex (rat MUC4), a multifunctional anti-adhesive glycoprotein

21 January 2018

1 reference

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Sialomucin complex, a heterodimeric glycoprotein complex. Expression as a soluble, secretable form in lactating mammary gland and colon

21 January 2018

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MUC4 expression increases progressively in pancreatic intraepithelial neoplasia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M603225200

1 reference

19 September 2017

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