Sitosterol-containing lipoproteins trigger free sterol-induced caspase-independent death in ACAT-competent macrophages (Q40293819)

19 September 2017

Sitosterol-containing lipoproteins trigger free sterol-induced caspase-independent death in ACAT-competent macrophages (English)

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19 September 2017

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Liping Bao

1

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19 September 2017

Yankun Li

2

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19 September 2017

Shi-Xian Deng

3

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19 September 2017

Donald Landry

4

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19 September 2017

Ira Tabas

5

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19 September 2017

language of work or name

English

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publication date

24 August 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

44

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19 September 2017

33635-33649

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Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

19 September 2017

1 reference

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A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol

21 January 2018

1 reference

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Sitosterolemia--a rare disease. Are elevated plant sterols an additional risk factor?

21 January 2018

1 reference

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Hyperapobetalipoproteinaemia in two families with xanthomas and phytosterolaemia

21 January 2018

1 reference

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No association between plasma levels of plant sterols and atherosclerosis in mice and men.

21 January 2018

1 reference

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Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations

21 January 2018

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Toxicity of sitosterol to human umbilical vein endothelial cells in vitro

21 January 2018

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Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endarterectomy

21 January 2018

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Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters

21 January 2018

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Cell biology of atherosclerosis

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Atherosclerosis. the road ahead

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21 January 2018

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Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis

21 January 2018

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Pathologic assessment of the vulnerable human coronary plaque

21 January 2018

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34th Bethesda Conference: Task force #2--What is the pathologic basis for new atherosclerosis imaging techniques?

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From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.

21 January 2018

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Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency

21 January 2018

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Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques

21 January 2018

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Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages

21 January 2018

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Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis

21 January 2018

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The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

21 January 2018

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Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions

21 January 2018

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Effect of ACAT inhibition on the progression of coronary atherosclerosis

21 January 2018

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The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction

21 January 2018

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NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.

21 January 2018

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Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol

21 January 2018

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

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THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

21 January 2018

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Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts

21 January 2018

1 reference

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Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor

21 January 2018

1 reference

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Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

21 January 2018

1 reference

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Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and a

21 January 2018

1 reference

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Acyl-coenzyme A:cholesterol acyltransferase

21 January 2018

1 reference

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Free cholesterol loading of macrophages induces apoptosis involving the fas pathway.

21 January 2018

1 reference

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Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia

21 January 2018

1 reference

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Optimisation of plant sterols incorporation in human keratinocyte plasma membrane and modulation of membrane fluidity.

21 January 2018

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Membrane properties of plant sterols in phospholipid bilayers as determined by differential scanning calorimetry, resonance energy transfer and detergent-induced solubilization

21 January 2018

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Fatty acid desaturase activities are modulated by phytosterol incorporation in microsomes

21 January 2018

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Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts). Comparison of cholesterol to plant, fungal, and disease-associated sterols and comparison of sphingomyelin, cerebrosides, a

21 January 2018

1 reference

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Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

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Anion-exchange blocker enhances cytoplasmic vacuole formation and cell death in serum-deprived mouse kidney epithelial cells in mice

21 January 2018

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Phytosterols decrease prostaglandin release in cultured P388D1/MAB macrophages

21 January 2018

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Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women

21 January 2018

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Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: results of a nested case-control analysis of the Prospective Cardiovascular Münster (PROCAM) study

21 January 2018

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Serum plant sterols as a potential risk factor for coronary heart disease

21 January 2018

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Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study. Finnish 4S Investigators

21 January 2018

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Cellular cholesterol efflux mediated by cyclodextrins. Demonstration Of kinetic pools and mechanism of efflux.

21 January 2018

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Modulation of membrane function by cholesterol.

21 January 2018

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Role of cholesterol and lipid organization in disease

21 January 2018

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Dual roles for cholesterol in mammalian cells

21 January 2018

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More than one way to die: apoptosis, necrosis and reactive oxygen damage

21 January 2018

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Death by design: apoptosis, necrosis and autophagy

21 January 2018

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Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

21 January 2018

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

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In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note

21 January 2018

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Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

21 January 2018

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Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

21 January 2018

1 reference

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Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the Mer receptor

21 January 2018

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Phorbol myristate acetate induces neutrophil death through activation of p38 mitogen-activated protein kinase that requires endogenous reactive oxygen species other than HOCl

21 January 2018

1 reference

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Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

21 January 2018

1 reference

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The role of the death-domain kinase RIP in tumour-necrosis-factor-induced activation of mitogen-activated protein kinases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M606339200

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19 September 2017

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