Intracerebroventricular administration of α-ketoisocaproic acid decreases brain-derived neurotrophic factor and nerve growth factor levels in brain of young rats (Q40300205)

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scientific article published on 20 November 2015

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English	Intracerebroventricular administration of α-ketoisocaproic acid decreases brain-derived neurotrophic factor and nerve growth factor levels in brain of young rats	scientific article published on 20 November 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Intracerebroventricular administration of α-ketoisocaproic acid decreases brain-derived neurotrophic factor and nerve growth factor levels in brain of young rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

object named as

Giselli Scaini

7

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author name string

Miriam S W Wisniewski

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Milena Carvalho-Silva

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Lara M Gomes

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Hugo G Zapelini

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Patrícia F Schuck

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Gustavo C Ferreira

6

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Europe PubMed Central

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19 September 2017

Emilio L Streck

8

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

publication date

20 November 2015

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Europe PubMed Central

PubMed publication ID

19 September 2017

Metabolic Brain Disease

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Europe PubMed Central

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19 September 2017

31

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Europe PubMed Central

PubMed publication ID

19 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

377-383

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Europe PubMed Central

PubMed publication ID

19 September 2017

Alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Reduction of large neutral amino acid levels in plasma and brain of hyperleucinemic rats.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Oxidative stress in plasma from maple syrup urine disease patients during treatment.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Amino acids levels and lipid peroxidation in maple syrup urine disease patients.

1 reference

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21 January 2018

Increased pro-nerve growth factor and decreased brain-derived neurotrophic factor in non-Alzheimer's disease tauopathies

1 reference

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21 January 2018

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

alpha-keto acids accumulating in maple syrup urine disease stimulate lipid peroxidation and reduce antioxidant defences in cerebral cortex from young rats.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity.

1 reference

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21 January 2018

Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

1 reference

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21 January 2018

Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor

1 reference

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21 January 2018

NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes

1 reference

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21 January 2018

Intrahippocampal administration of the alpha-keto acids accumulating in maple syrup urine disease provokes learning deficits in rats

1 reference

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21 January 2018

Distinct effects of p75 in mediating actions of neurotrophins on basal forebrain oligodendrocytes

1 reference

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21 January 2018

A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex

1 reference

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21 January 2018

The intra-hippocampal leucine administration impairs memory consolidation and LTP generation in rats

1 reference

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21 January 2018

Recombinant human NGF-loaded microspheres promote survival of basal forebrain cholinergic neurons and improve memory impairments of spatial learning in the rat model of Alzheimer's disease with fimbria-fornix lesion

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis

1 reference

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21 January 2018

Neurotrophins: roles in neuronal development and function

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Different effects of oxidative stress on activation of transcription factors in primary cultured rat neuronal and glial cells

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

MR diffusion imaging and MR spectroscopy of maple syrup urine disease during acute metabolic decompensation

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Glutamate elicits release of BDNF from basal forebrain astrocytes in a process dependent on metabotropic receptors and the PLC pathway

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome c release: implications for neurological impairment associated with maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Structural white matter changes in adolescents and young adults with maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Regulation of cell survival by secreted proneurotrophins

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Neurotrophin secretory pathways and synaptic plasticity

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

The yin and yang of neurotrophin action

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory?

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

The nerve growth factor family of receptors

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Neurotrophins and synaptic plasticity in the mammalian spinal cord.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Protein and lipid damage in maple syrup urine disease patients: l-carnitine effect

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Neurotrophin-regulated signalling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Evaluation of acetylcholinesterase in an animal model of maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

DNA damage in an animal model of maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Antioxidant administration prevents memory impairment in an animal model of maple syrup urine disease

1 reference

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21 January 2018

Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Acute and chronic administration of the branched-chain amino acids decreases nerve growth factor in rat hippocampus

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Acute Administration of Branched-Chain Amino Acids Increases the Pro-BDNF/Total-BDNF Ratio in the Rat Brain

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Dysmyelination in the brain of adolescents and young adults with maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Glutamate stimulates neurotrophin expression in cultured Müller cells

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Maple syrup urine disease: interrelations between branched-chain amino-, oxo- and hydroxyacids; implications for treatment; associations with CNS dysmyelination

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Myelin proteins: degradation in rat brain initiated by metabolites causative of maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

The role of neurotrophins in neurotransmitter release

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Intrahippocampal administration of the branched-chain alpha-hydroxy acids accumulating in maple syrup urine disease compromises rat performance in aversive and non-aversive behavioral tasks

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Cross talk between vestibular neurons and Schwann cells mediates BDNF release and neuronal regeneration.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Reduction of plasma concentrations of large neutral amino acids in patients with maple syrup urine disease during crises

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Reduction of large neutral amino acid concentrations in plasma and CSF of patients with maple syrup urine disease during crises

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Neurocognitive profile in a case of maple syrup urine disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Large neutral amino acids auto exchange when infused by microdialysis into the rat brain: implication for maple syrup urine disease and phenylketonuria

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Region-Specific Neurotrophin Imbalances in Alzheimer Disease

1 reference

https://api.crossref.org/works/10.1007%2FS11011-015-9768-8

21 January 2018

Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor promotes central nervous system myelination via a direct effect upon oligodendrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of amino acids in the interstitial space of the rat brain following infusion of large neutral amino and keto acids by microdialysis: alpha-ketoisocaproate infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of brain energy metabolism by the branched-chain amino acids accumulating in maple syrup urine disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal protein and lipid compositions of the cerebral myelin of a patient with maple syrup urine disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of alpha-ketoacids on the respiration of brain in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain and Serum Levels of Nerve Growth Factor in a Rat Model of Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAPLE SYRUP URINE DISEASE, WITH PARTICULAR REFERENCE TO DIETOTHERAPY

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary human fibroblasts from a maple syrup urine disease patient undergo apoptosis following exposure to physiological concentrations of branched chain amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/26586008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11011-015-9768-8

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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