Genetic targeting of adenovirus vectors using a reovirus sigma1-based attachment protein (Q40309058)

19 September 2017

title

Genetic targeting of adenovirus vectors using a reovirus sigma1-based attachment protein (English)

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19 September 2017

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Frederik H E Schagen

1

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19 September 2017

Felix M Wensveen

2

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19 September 2017

Jan E Carette

3

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19 September 2017

Terence S Dermody

4

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19 September 2017

Winald R Gerritsen

5

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19 September 2017

Victor W van Beusechem

6

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19 September 2017

publication date

3 March 2006

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19 September 2017

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19 September 2017

volume

13

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19 September 2017

issue

5

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19 September 2017

page(s)

997-1005

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What does it take to bind CAR?

19 September 2017

cites work

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Integrin alpha(v)beta1 is an adenovirus coreceptor

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Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization.

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Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

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Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

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Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions

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Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation

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Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice

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The influence of adenovirus fiber structure and function on vector development for gene therapy

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Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions

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Genetic targeting of adenoviral vectors

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Targeted adenoviral vectors

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Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

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Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

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Recombinant adenovirus vectors with knobless fibers for targeted gene transfer

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Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber

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Genetic targeting of an adenovirus vector via replacement of the fiber protein with the phage T4 fibritin

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Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors

7 January 2021

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Genetically targeted adenovirus vector directed to CD40-expressing cells

7 January 2021

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Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber

7 January 2021

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Junction adhesion molecule is a receptor for reovirus

7 January 2021

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The N-terminal heptad repeat region of reovirus cell attachment protein sigma 1 is responsible for sigma 1 oligomer stability and possesses intrinsic oligomerization function

7 January 2021

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The incorporation of reovirus cell attachment protein sigma 1 into virions requires the N-terminal hydrophobic tail and the adjacent heptad repeat region

7 January 2021

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The N-terminal quarter of reovirus cell attachment protein sigma 1 possesses intrinsic virion-anchoring function

7 January 2021

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Rescue and propagation of fully retargeted oncolytic measles viruses

7 January 2021

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A system for the propagation of adenoviral vectors with genetically modified receptor specificities

7 January 2021

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Unfolding studies of human adenovirus type 2 fibre trimers. Evidence for a stable domain

7 January 2021

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The reovirus cell attachment protein possesses two independently active trimerization domains: basis of dominant negative effects

7 January 2021

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A chimeric adenovirus vector encoding reovirus attachment protein sigma1 targets cells expressing junctional adhesion molecule 1.

7 January 2021

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Reovirus sigma1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathway

7 January 2021

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Complementation of a fibre mutant adenovirus by packaging cell lines stably expressing the adenovirus type 5 fibre protein

7 January 2021

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Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

7 January 2021

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Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion

7 January 2021

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Improved adenovirus vectors for infection of cardiovascular tissues

7 January 2021

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A simplified system for generating recombinant adenoviruses

7 January 2021

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Replication-dependent transgene expression from a conditionally replicating adenovirus via alternative splicing to a heterologous splice-acceptor site.

7 January 2021

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Evidence for functional domains on the reovirus type 3 hemagglutinin

7 January 2021

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Targeted gene delivery by tropism-modified adenoviral vectors

7 January 2021

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Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.11.019

inferred from DOI database lookup

7 January 2021

based on heuristic

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.11.019

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMTHE.2005.11.019

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19 September 2017

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