Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major. (Q40312214)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16497676%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major (English)

1 reference

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17 January 2020

main subject

autophagy

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1 reference

GeneDB

AUT2/APG4/ATG4 cysteine peptidase, putative

6 February 2019

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GeneDB

6 February 2019

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1

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17 January 2020

Roderick Williams

2

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17 January 2020

Jeremy C. Mottram

5

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17 January 2020

author name string

Lesley S Morrison

3

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17 January 2020

Graham H Coombs

4

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17 January 2020

language of work or name

English

0 references

publication date

23 February 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16497676%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 January 2020

published in

1 reference

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17 January 2020

volume

281

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17 January 2020

page(s)

11384-11396

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17 January 2020

issue

16

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Regulated portals of entry into the cell

17 January 2020

cites work

1 reference

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Receptor downregulation and multivesicular-body sorting

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Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants

21 January 2018

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Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant

21 January 2018

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Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

21 January 2018

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Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

21 January 2018

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

21 January 2018

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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

21 January 2018

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The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells

21 January 2018

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The flagellum and flagellar pocket of trypanosomatids

21 January 2018

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Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocket

21 January 2018

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Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana

21 January 2018

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Secretory and endocytic pathways converge in a dynamic endosomal system in a primitive protozoan

21 January 2018

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Rab5-mediated endosome-endosome fusion regulates hemoglobin endocytosis in Leishmania donovani

21 January 2018

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Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

21 January 2018

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

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Autophagy in the eukaryotic cell

21 January 2018

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Approaching the molecular mechanism of autophagy

21 January 2018

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Autophagosome formation in mammalian cells

21 January 2018

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SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation

21 January 2018

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Mutational analysis of Csc1/Vps4p: involvement of endosome in regulation of autophagy in yeast

21 January 2018

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Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

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Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae

21 January 2018

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A new expression vector for Crithidia fasciculata and Leishmania

21 January 2018

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Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

21 January 2018

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A modified colorimetric assay of macrophage activation for intracellular cytotoxicity against Leishmania parasites

21 January 2018

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A potential role for ICP, a Leishmanial inhibitor of cysteine peptidases, in the interaction between host and parasite

21 January 2018

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Expression of a hydrophilic surface protein in infective stages of Leishmania major

21 January 2018

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Characterization of a differentially expressed protein that shows an unusual localization to intracellular membranes in Leishmania major

21 January 2018

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The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment

21 January 2018

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ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking

21 January 2018

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Endocytosis, membrane recycling and sorting of GPI-anchored proteins: Trypanosoma brucei as a model system

21 January 2018

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The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation

21 January 2018

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A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

21 January 2018

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Identification of an infective stage of Leishmania promastigotes.

21 January 2018

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Autophagy and related processes in trypanosomatids: insights from genomic and bioinformatic analyses

21 January 2018

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Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

21 January 2018

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A ubiquitin-like system mediates protein lipidation

21 January 2018

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Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex

21 January 2018

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The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

21 January 2018

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A specialized pathway affecting virulence glycoconjugates of Leishmania.

21 January 2018

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Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae

21 January 2018

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A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

21 January 2018

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Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M512307200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16497676%20AND%20SRC:MED&resulttype=core&format=json

release_rpe447a3ozdhhcijulojrxecyu

17 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/rpe447a3ozdhhcijulojrxecyu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference