Uptake and efflux transporters for conjugates in human hepatocytes (Q40332779)

19 September 2017

title

Uptake and efflux transporters for conjugates in human hepatocytes (English)

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19 September 2017

Dietrich Keppler

1

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19 September 2017

language of work or name

English

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publication date

1 January 2005

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19 September 2017

published in

Methods in Enzymology

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19 September 2017

volume

400

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19 September 2017

page(s)

531-542

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Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1

19 September 2017

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cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

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Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion

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Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

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Expression cloning of a rat liver Na(+)-independent organic anion transporter

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Selective hepatobiliary transport defect for organic anions and neutral steroids in mutant rats with hereditary-conjugated hyperbilirubinemia

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

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Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2.

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Transport function and substrate specificity of multidrug resistance protein

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A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

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Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide

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Identification and functional characterization of the natural variant MRP3-Arg1297His of human multidrug resistance protein 3 (MRP3/ABCC3).

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Vectorial transport of the peptide CCK-8 by double-transfected MDCKII cells stably expressing the organic anion transporter OATP1B3 (OATP8) and the export pump ABCC2.

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Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

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Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)

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7 January 2021

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7 January 2021

The multispecific organic anion transporter (OAT) family.

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7 January 2021

Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

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7 January 2021

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

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7 January 2021

Isolation of a family of organic anion transporters from human liver and kidney

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7 January 2021

ABCG2 transports sulfated conjugates of steroids and xenobiotics

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Kinetic analysis of hepatobiliary transport for conjugated metabolites in the perfused liver of mutant rats (EHBR) with hereditary conjugated hyperbilirubinemia

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Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

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7 January 2021

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Identifiers

DOI

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19 September 2017

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