Development and exploitation of CK2 inhibitors (Q40342605)

19 September 2017

Development and exploitation of CK2 inhibitors (English)

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19 September 2017

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19 September 2017

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19 September 2017

Marco Mazzorana

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Mario A Pagano

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Mario A Pagano

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Alfonso Zambon

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Alfonso Zambon

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Stefania Sarno

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Stefania Sarno

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author name string

Pietrogiulio Frascella

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19 September 2017

Flavio Meggio

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19 September 2017

Vittorio Lucchini

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19 September 2017

Lorenzo A Pinna

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19 September 2017

1 June 2005

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Molecular and Cellular Biochemistry

19 September 2017

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19 September 2017

274

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19 September 2017

1-2

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19 September 2017

69-76

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https://scigraph.springernature.com/pub.10.1007/s11010-005-3079-z

19 September 2017

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cites work

Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

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Crossref

https://api.crossref.org/works/10.1007%2FS11010-005-3079-Z

Protein Kinase CK2 Mutants Defective in Substrate Recognition

21 January 2018

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12 December 2020

Protein kinase CK2 phosphorylates the cell cycle regulatory protein Geminin.

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12 December 2020

The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks

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12 December 2020

Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight

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12 December 2020

Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle.

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12 December 2020

Active and inactive protein kinases: structural basis for regulation

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12 December 2020

Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.

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12 December 2020

CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism

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12 December 2020

Protein kinase CK2: a challenge to canons

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12 December 2020

Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

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12 December 2020

Unique activation mechanism of protein kinase CK2. The N-terminal segment is essential for constitutive activity of the catalytic subunit but not of the holoenzyme

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12 December 2020

Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK

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12 December 2020

Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)

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12 December 2020

Protein kinase CKIIα interacts with the Bcr moiety of Bcr/Abl and mediates proliferation of Bcr/Abl-expressing cells

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12 December 2020

Protein kinase CK2 signal in neoplasia

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12 December 2020

2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.

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12 December 2020

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

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12 December 2020

Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

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12 December 2020

Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study

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12 December 2020

Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole

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12 December 2020

Discovery of a potent and selective protein kinase CK2 inhibitor by high-throughput docking

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12 December 2020

Elevated protein kinase CK2 activity in chromatin of head and neck tumors: association with malignant transformation.

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12 December 2020

Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties.

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12 December 2020

Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

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12 December 2020

p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice.

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12 December 2020

A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells

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12 December 2020

Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization

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12 December 2020

CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37.

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12 December 2020

One-thousand-and-one substrates of protein kinase CK2?

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12 December 2020

Expression of the Stp1 LMW-PTP and inhibition of protein CK2 display a cooperative effect on immunophilin Fpr3 tyrosine phosphorylation and Saccharomyces cerevisiae growth.

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12 December 2020

The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2

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12 December 2020

10.1007/S11010-005-3079-Z

Identifiers

DOI

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19 September 2017

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