Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration (Q40349274)

19 September 2017

Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration (English)

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19 September 2017

Zhong-Sheng Ji

1

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19 September 2017

Karin Müllendorff

2

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19 September 2017

Irene H Cheng

3

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19 September 2017

R Dennis Miranda

4

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19 September 2017

Yadong Huang

5

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19 September 2017

Robert W Mahley

6

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19 September 2017

language of work or name

English

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publication date

17 November 2005

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

2683-2692

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19 September 2017

5

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E: far more than a lipid transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Age at onset in two common neurodegenerative diseases is genetically controlled

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E and presenilin-1 genotypes in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

APOE genotype influences acquisition and recall following traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Familial dementia with lewy bodies: a clinical and neuropathological study of 2 families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Cognitive change and the APOE epsilon 4 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Influence of apolipoprotein E genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Brain-derived neurotrophic factor, apolipoprotein E genetic variants and cognitive performance in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Six-month recovery from mild to moderate Traumatic Brain Injury: the role of APOE-epsilon4 allele.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Mechanisms of neuronal degeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E dose-dependent modulation of beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E modulates gamma-secretase cleavage of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Self-assembly of Abeta(1-42) into globular neurotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Protofibrils of amyloid beta-protein inhibit specific K+ currents in neocortical cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

21 January 2018

Lysosomes in cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

LRP and senile plaques in Alzheimer's disease: colocalization with apolipoprotein E and with activated astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Intraneuronal Abeta42 accumulation in human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

The structural basis of protein folding and its links with human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Acidic pH promotes the formation of toxic fibrils from beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

pH-Dependent Amyloid and Protofibril Formation by the ABri Peptide of Familial British Dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

The Arctic mutation interferes with processing of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Mutations that reduce aggregation of the Alzheimer's Abeta42 peptide: an unbiased search for the sequence determinants of Abeta amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against beta-amyloid-mediated effects on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Effect of alkalizing agents on the processing of the beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Intralysosomal iron: a major determinant of oxidant-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Structure and properties of the vacuolar (H+)-ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Lysosomal biogenesis in lysosomal storage disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Beta-amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

APOE and the risk of PD with or without dementia in a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506646200

21 January 2018

Identifiers

DOI

10.1074/JBC.M506646200

1 reference

19 September 2017

1 reference