Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. (Q40367630)

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scientific article published on September 2005

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English	Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism.	scientific article published on September 2005

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scholarly article

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7 January 2020

Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism (English)

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7 January 2020

David E Clapham

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7 January 2020

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Haoxing Xu

1

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7 January 2020

Nathaniel T Blair

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7 January 2020

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1 September 2005

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7 January 2020

Journal of Neuroscience

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7 January 2020

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7 January 2020

8924-8937

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7 January 2020

39

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7 January 2020

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

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Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Acid potentiation of the capsaicin receptor determined by a key extracellular site

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of vanilloid receptor channel activity by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capsaicin inhibits activation of voltage-gated sodium currents in capsaicin-sensitive trigeminal ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Differences in sensitivity of vanilloid receptor 1 transfected to human embryonic kidney cells and capsaicin-activated channels in cultured rat dorsal root ganglion neurons to capsaicin receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Molecular basis for species-specific sensitivity to "hot" chili peppers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Identification of a cold receptor reveals a general role for TRP channels in thermosensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A TRP channel that senses cold stimuli and menthol

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A heat-sensitive TRP channel expressed in keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRPV3 is a calcium-permeable temperature-sensitive cation channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of permeation through the cation channel TRPV4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage-dependent priming of rat vanilloid receptor: effects of agonist and protein kinase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tyrosine residue in TM6 of the Vanilloid Receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ThermoTRP channels and beyond: mechanisms of temperature sensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contact irritant dermatitis and anti-pruritic agents: the need to address the itch

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lessons from peppers and peppermint: the molecular logic of thermosensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anandamide and vanilloid TRPV1 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Tetrodotoxin-Resistant Na+Current Slow Inactivation in Adaptation of Action Potential Firing in Small-Diameter Dorsal Root Ganglion Neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRP channels as cellular sensors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The analgesic effect induced by capsaicin is enhanced in inflammatory states

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction for liquid junction potentials in patch clamp experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational mechanisms of peripheral sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell signaling and the genesis of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

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Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forty years in capsaicin research for sensory pharmacology and physiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRPV1b, a functional human vanilloid receptor splice variant

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphasic currents evoked by chemical or thermal activation of the heat-gated ion channel, TRPV3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TRP superfamily of cation channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensory characteristics of camphor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of camphor, eucalyptus and menthol vapour on nasal resistance to airflow and nasal sensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cloned capsaicin receptor integrates multiple pain-producing stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/16192383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2574-05.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192383%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192383%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16192383%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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