Direct random insertion of an influenza virus immunologic determinant into the NS1 glycoprotein of a vaccine flavivirus (Q40374118)

19 September 2017

Direct random insertion of an influenza virus immunologic determinant into the NS1 glycoprotein of a vaccine flavivirus (English)

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19 September 2017

8

Farshad Guirakhoo

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19 September 2017

Alexander A Rumyantsev

1

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19 September 2017

Zhen-xi Zhang

2

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19 September 2017

Qing-sheng Gao

3

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19 September 2017

Nicolas Moretti

4

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19 September 2017

Nathan Brown

5

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19 September 2017

Harold Kleanthous

6

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19 September 2017

Simon Delagrave

7

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19 September 2017

Marc S Collett

9

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19 September 2017

Konstantin V Pugachev

10

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19 September 2017

language of work or name

English

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publication date

12 November 2009

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19 September 2017

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19 September 2017

396

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19 September 2017

2

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19 September 2017

329-338

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Development of Sindbis Viruses Encoding nsP2/GFP Chimeric Proteins and Their Application for Studying nsP2 Functioning

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Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes

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Surface expression of an immunodominant malaria protein B cell epitope by yellow fever virus

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Expression of foreign protein epitopes at the surface of recombinant yellow fever 17D viruses based on three-dimensional modeling of its envelope protein.

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A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

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Rapid identification of essential and nonessential herpesvirus genes by direct transposon mutagenesis

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Ab and T cell epitopes of influenza A virus, knowledge and opportunities

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West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

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In situ reactions of monoclonal antibodies with a viable mutant of Murray Valley encephalitis virus reveal an absence of dimeric NS1 protein

7 January 2021

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The NS1 protein of tick-borne encephalitis virus forms multimeric species upon secretion from the host cell

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Role of the hypervariable hinge region of phosphoprotein P of vesicular stomatitis virus in viral RNA synthesis and assembly of infectious virus particles

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Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies.

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A "universal" human influenza A vaccine

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Random insertion mutagenesis of sindbis virus nonstructural protein 2 and selection of variants incapable of downregulating cellular transcription

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Comparative immunogenicity evaluations of influenza A virus M2 peptide as recombinant virus like particle or conjugate vaccines in mice and monkeys

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Heterologous gene expression by infectious and replicon vectors derived from tick-borne encephalitis virus and direct comparison of this flavivirus system with an alphavirus replicon

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Immunogenicity, genetic stability, and protective efficacy of a recombinant, chimeric yellow fever-Japanese encephalitis virus (ChimeriVax-JE) as a live, attenuated vaccine candidate against Japanese encephalitis

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Construction, safety, and immunogenicity in nonhuman primates of a chimeric yellow fever-dengue virus tetravalent vaccine

7 January 2021

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Viremia and immunogenicity in nonhuman primates of a tetravalent yellow fever-dengue chimeric vaccine: genetic reconstructions, dose adjustment, and antibody responses against wild-type dengue virus isolates

7 January 2021

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Live attenuated chimeric yellow fever dengue type 2 (ChimeriVax-DEN2) vaccine: Phase I clinical trial for safety and immunogenicity: effect of yellow fever pre-immunity in induction of cross neutralizing antibody responses to all 4 dengue serotypes.

7 January 2021

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Loss of dimerisation of the nonstructural protein NS1 of Kunjin virus delays viral replication and reduces virulence in mice, but still allows secretion of NS1.

7 January 2021

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Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

7 January 2021

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Influenza A vaccine based on the extracellular domain of M2: weak protection mediated via antibody-dependent NK cell activity.

7 January 2021

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Construction and applications of yellow fever virus replicons.

7 January 2021

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Molecular biology of flaviviruses

7 January 2021

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Recombinant yellow fever viruses are effective therapeutic vaccines for treatment of murine experimental solid tumors and pulmonary metastases

7 January 2021

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Chimeric live, attenuated vaccine against Japanese encephalitis (ChimeriVax-JE): phase 2 clinical trials for safety and immunogenicity, effect of vaccine dose and schedule, and memory response to challenge with inactivated Japanese encephalitis anti

7 January 2021

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A live, attenuated recombinant West Nile virus vaccine

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Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

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Functional characterization of the Sindbis virus E2 glycoprotein by transposon linker-insertion mutagenesis

7 January 2021

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A universal influenza A vaccine based on the extracellular domain of the M2 protein

7 January 2021

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Pulmonary immunity and immunopathology: lessons from respiratory syncytial virus.

7 January 2021

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Restricted replication and lysosomal trafficking of yellow fever 17D vaccine virus in human dendritic cells.

7 January 2021

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Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applications

7 January 2021

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Traditional and novel approaches to flavivirus vaccines

7 January 2021

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Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

7 January 2021

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A novel method for cloning of non-cytolytic viruses.

7 January 2021

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Mutation of E1 glycoprotein of classical swine fever virus affects viral virulence in swine.

7 January 2021

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A tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient mice

7 January 2021

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Protection of mice against dengue 2 virus encephalitis by immunization with the dengue 2 virus non-structural glycoprotein NS1.

7 January 2021

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Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments.

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Yellow fever 17D as a vaccine vector for microbial CTL epitopes

7 January 2021

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Genetic vaccination of mice with plasmids encoding the NS1 non-structural protein from tick-borne encephalitis virus and dengue 2 virus

7 January 2021

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West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction

7 January 2021

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Evidence that the mature form of the flavivirus nonstructural protein NS1 is a dimer

7 January 2021

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Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion

7 January 2021

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Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function.

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Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation

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Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice

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7 January 2021

10.1016/J.VIROL.2009.10.033

Identifiers

DOI

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19 September 2017

1 reference