Evolution of constrained gonadotropin-releasing hormone ligand conformation and receptor selectivity (Q40374579)

19 September 2017

title

Evolution of constrained gonadotropin-releasing hormone ligand conformation and receptor selectivity (English)

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10

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Zhi-Liang Lu

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Adam J Pawson

object named as

Adam J Pawson

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Takehiro Kusakabe

object named as

Takehiro Kusakabe

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author name string

Perdita E Barran

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Roger W Roeske

2

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Robin Sellar

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Michael T Bowers

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Kevin Morgan

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Motoyuki Tsuda

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language of work or name

English

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publication date

12 September 2005

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Journal of Biological Chemistry

19 September 2017

published in

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volume

280

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19 September 2017

issue

46

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19 September 2017

page(s)

38569-38575

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Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor

19 September 2017

cites work

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Two new forms of gonadotropin-releasing hormone in a protochordate and the evolutionary implications

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Sequence of two gonadotropin releasing hormones from tunicate suggest an important role of conformation in receptor activation

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Gonadotropin-releasing hormone receptors

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Six novel gonadotropin-releasing hormones are encoded as triplets on each of two genes in the protochordate, Ciona intestinalis.

21 January 2018

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Isolation and characterization of a GnRH-like peptide from Octopus vulgaris

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Gonadotropin-releasing hormone analog design. Structure-function studies toward the development of agonists and antagonists: rationale and perspective

21 January 2018

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Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl-terminal tail Are critical

21 January 2018

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Follistatins: more than follicle-stimulating hormone suppressing proteins

21 January 2018

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A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants

21 January 2018

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Two gonadotropin-releasing hormone receptors in the African catfish: no differences in ligand selectivity, but differences in tissue distribution

21 January 2018

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Structure, expression, and cluster organization of genes encoding gonadotropin-releasing hormone receptors found in the neural complex of the ascidian Ciona intestinalis

21 January 2018

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21 January 2018

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Synthetic analogs of the hypothalamic luteinizing hormone releasing factor with increased agonist or antatonist properties

21 January 2018

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Asn102 of the gonadotropin-releasing hormone receptor is a critical determinant of potency for agonists containing C-terminal glycinamide

21 January 2018

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Mutations remote from the human gonadotropin-releasing hormone (GnRH) receptor-binding sites specifically increase binding affinity for GnRH II but not GnRH I: evidence for ligand-selective, receptor-active conformations.

21 January 2018

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Gonadotropin-releasing hormone in mulberry cells of Saccoglossus and Ptychodera (Hemichordata: Enteropneusta).

21 January 2018

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Differential G protein coupling preference of mammalian and nonmammalian gonadotropin-releasing hormone receptors

21 January 2018

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Tunicate gonadotropin-releasing hormone (GnRH) peptides selectively activate Ciona intestinalis GnRH receptors and the green monkey type II GnRH receptor.

21 January 2018

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Structural investigation of naturally occurring peptides by electron capture dissociation and AMBER force field modelling

21 January 2018

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Conformational Constraint of Mammalian, Chicken, and Salmon GnRHs, But Not GnRH II, Enhances Binding at Mammalian and Nonmammalian Receptors: Evidence for Preconfiguration of GnRH II

21 January 2018

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A Locus of the Gonadotropin-releasing Hormone Receptor That Differentiates Agonist and Antagonist Binding Sites

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M503086200

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19 September 2017

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