A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2). (Q40398708)

20 September 2017

title

A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2). (English)

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20 September 2017

main subject

transmembrane protein

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author name string

Xiaohong Zhang

1

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20 September 2017

Nikhil V Shirahatti

2

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20 September 2017

Daruka Mahadevan

3

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20 September 2017

Stephen H Wright

4

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20 September 2017

language of work or name

English

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publication date

8 August 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

41

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20 September 2017

page(s)

34813-34822

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Molecular and cellular physiology of renal organic cation and anion transport

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Cloning and characterization of two human polyspecific organic cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Drug excretion mediated by a new prototype of polyspecific transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Cloning of the mouse organic cation transporter 2 gene, Slc22a2, from an enhancer-trap transgene integration locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Cloning and functional expression of a mouse liver organic cation transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Molecular cloning and functional expression of a rabbit renal organic cation transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Restart procedures for the conjugate gradient method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

WHAT IF: a molecular modeling and drug design program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Deviations from standard atomic volumes as a quality measure for protein crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

NBD-TMA: a novel fluorescent substrate of the peritubular organic cation transporter of renal proximal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Structure and mechanism of the lactose permease of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Structural conservation in the major facilitator superfamily as revealed by comparative modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Role of glycosylation in the organic anion transporter OAT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Evaluation and application of multiple scoring functions for a virtual screening experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

A knowledge-based energy function for protein-ligand, protein-protein, and protein-DNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecu

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506342200

21 January 2018

Identifiers

DOI

10.1074/JBC.M506342200

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20 September 2017

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