Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis (Q40399203)

20 September 2017

Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis (English)

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20 September 2017

4

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20 September 2017

Jodie L Guy

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20 September 2017

Richard M Jackson

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2

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20 September 2017

Hanne A Jensen

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3

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20 September 2017

Anthony J Turner

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5

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20 September 2017

language of work or name

English

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publication date

1 July 2005

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20 September 2017

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20 September 2017

272

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14

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20 September 2017

3512-3520

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describes a project that uses

20 September 2017

site-directed mutagenesis

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A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

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cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Angiotensin-converting enzyme 2 is an essential regulator of heart function

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Crystal structure of the human angiotensin-converting enzyme-lisinopril complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Measurement of protein using bicinchoninic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Enhanced Renal Immunocytochemical Expression of ANG-(1-7) and ACE2 During Pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04756.X

Pregnancy enhances the angiotensin (Ang)-(1-7) vasodilator response in mesenteric arteries and increases the renal concentration and urinary excretion of Ang-(1-7).

21 January 2018

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12 December 2020

Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus

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12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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12 December 2020

Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme.

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12 December 2020

Arg(1098) is critical for the chloride dependence of human angiotensin I-converting enzyme C-domain catalytic activity.

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12 December 2020

Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins

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12 December 2020

ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis

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12 December 2020

Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril

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12 December 2020

Novel peptide inhibitors of angiotensin-converting enzyme 2.

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12 December 2020

Angiotensin I-converting enzyme transition state stabilization by HIS1089: evidence for a catalytic mechanism distinct from other gluzincin metalloproteinases

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12 December 2020

Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination?

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12 December 2020

Membrane-associated zinc peptidase families: comparing ACE and ACE2.

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12 December 2020

Structure-function discrimination of the N- and C- catalytic domains of human angiotensin-converting enzyme: implications for Cl- activation and peptide hydrolysis mechanisms.

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12 December 2020

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.

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12 December 2020

Structure-based discovery of a novel angiotensin-converting enzyme 2 inhibitor

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12 December 2020

Activation of angiotensin converting enzyme by monovalent anions

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12 December 2020

ACE2: from vasopeptidase to SARS virus receptor

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12 December 2020

10.1111/J.1742-4658.2005.04756.X

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DOI

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20 September 2017

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