The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity (Q40399626)

20 September 2017

The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity (English)

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20 September 2017

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9

Ann M Bode

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20 September 2017

10

Zigang Dong

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20 September 2017

4

Yong-Yeon Cho

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20 September 2017

6

Bong Seok Kang

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20 September 2017

Bu Young Choi

1

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20 September 2017

Hong Seok Choi

2

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20 September 2017

Kwangseok Ko

3

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20 September 2017

Feng Zhu

5

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20 September 2017

Svetlana P Ermakova

7

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20 September 2017

Wei-Ya Ma

8

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20 September 2017

10 July 2005

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Nature Structural & Molecular Biology

20 September 2017

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20 September 2017

12

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20 September 2017

8

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20 September 2017

699-707

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https://scigraph.springernature.com/pub.10.1038/nsmb960

20 September 2017

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cites work

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

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Parsing Ink4a/Arf: "pure" p16-null mice

21 January 2018

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

21 January 2018

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Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

21 January 2018

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Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

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Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

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Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets

21 January 2018

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The INK4a/ARF locus and melanoma

21 January 2018

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Regulation of transcription by MAP kinase cascades

21 January 2018

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Signal transduction by the JNK group of MAP kinases

21 January 2018

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

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JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate

21 January 2018

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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

21 January 2018

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Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

21 January 2018

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c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

21 January 2018

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

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JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

21 January 2018

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Molecular surface recognition: determination of geometric fit between proteins and their ligands by correlation techniques

21 January 2018

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Hydrophobic docking: a proposed enhancement to molecular recognition techniques.

21 January 2018

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Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4

21 January 2018

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Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

21 January 2018

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

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Adenovirus-mediated p16INK4 gene transfer significantly suppresses human breast cancer growth

21 January 2018

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Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

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The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

21 January 2018

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Regulation of JNK signaling by GSTp

21 January 2018

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Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

21 January 2018

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Function and regulation of AP-1 subunits in skin physiology and pathology

21 January 2018

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AP-1 in cell proliferation and survival

21 January 2018

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Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1.

21 January 2018

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Protein docking for low-resolution structures.

21 January 2018

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A systematic study of low-resolution recognition in protein--protein complexes

21 January 2018

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Biological assays for Ras transformation

21 January 2018

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Neonatal sunburn and melanoma in mice

21 January 2018

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Involvement of growth factor receptors in the mammalian UVC response

21 January 2018

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Sunlight and melanoma: an answer from MTS1 (p16)

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB960

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Dimensions Publication ID

20 September 2017

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