Systematic segregation to mutant mitochondrial DNA and accompanying loss of mitochondrial DNA in human NT2 teratocarcinoma Cybrids. (Q40412052)

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12 January 2020

title

Systematic segregation to mutant mitochondrial DNA and accompanying loss of mitochondrial DNA in human NT2 teratocarcinoma Cybrids (English)

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12 January 2020

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7

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12 January 2020

Ian Holt

9

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12 January 2020

author name string

Carrie J Turner

1

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12 January 2020

Caroline Granycome

2

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12 January 2020

Rachel Hurst

3

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12 January 2020

Elizabeth Pohler

4

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12 January 2020

M Katariina Juhola

5

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12 January 2020

Martti I Juhola

6

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Lesley Sutherland

8

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language of work or name

English

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publication date

8 June 2005

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12 January 2020

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12 January 2020

volume

170

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issue

4

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12 January 2020

page(s)

1879-1885

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Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells.

12 January 2020

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22 September 2017

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Skewed segregation of the mtDNA nt 8993 (T-->G) mutation in human oocytes

22 September 2017

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A new mtDNA mutation showing accumulation with time and restriction to skeletal muscle

22 September 2017

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Defective respiratory capacity and mitochondrial protein synthesis in transformant cybrids harboring the tRNA(Leu(UUR)) mutation associated with maternally inherited myopathy and cardiomyopathy

22 September 2017

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Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line

22 September 2017

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Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes.

22 September 2017

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A tridecamer DNA sequence supports human mitochondrial RNA 3'-end formation in vitro

22 September 2017

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Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

22 September 2017

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A new mitochondrial disease associated with mitochondrial DNA heteroplasmy

22 September 2017

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Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

22 September 2017

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Simplified mammalian DNA isolation procedure

22 September 2017

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In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria

22 September 2017

1 reference

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Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes

22 September 2017

1 reference

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MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts

22 September 2017

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Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy

22 September 2017

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Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells

22 September 2017

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Preferential amplification and phenotypic selection in a population of deleted and wild-type mitochondrial DNA in cultured cells

25 September 2017

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Intracellular heteroplasmy for disease-associated point mutations in mtDNA: implications for disease expression and evidence for mitotic segregation of heteroplasmic units of mtDNA

25 September 2017

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Fate and expression of the deleted mitochondrial DNA differ between human heteroplasmic skin fibroblast and Epstein-Barr virus-transformed lymphocyte cultures.

25 September 2017

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A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

15 June 2018

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Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

15 June 2018

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Heteroplasmic ratio of the A3243G mitochondrial DNA mutation in single pancreatic beta cells

15 June 2018

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Glutathione-S-transferase gene polymorphisms in colorectal cancer patients: interaction between GSTM1 and GSTM3 allele variants as a risk-modulating factor

20 August 2018

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20 August 2018

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20 August 2018

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Mitochondrial DNA, diabetes and pancreatic pathology in Kearns-Sayre syndrome

4 November 2018

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12 December 2020

Behaviour of a population of partially duplicated mitochondrial DNA molecules in cell culture: segregation, maintenance and recombination dependent upon nuclear background

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12 December 2020

A tRNA suppressor mutation in human mitochondria

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12 December 2020

Introduction of heteroplasmic mitochondrial DNA (mtDNA) from a patient with NARP into two human rho degrees cell lines is associated either with selection and maintenance of NARP mutant mtDNA or failure to maintain mtDNA

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12 December 2020

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

1 reference

12 December 2020

degSegregation of Mitochondrial DNAs Carrying a Pathogenic Point Mutation (tRNAleu3243) in Cybrid Cells

1 reference

12 December 2020

10.1534/GENETICS.105.043653

Identifiers

DOI

1 reference

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12 January 2020

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12 January 2020

PubMed publication ID

15944344

1 reference