A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha (Q40415755)

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English	A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha	scientific article

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scholarly article

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Europe PubMed Central

20 September 2017

A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms alpha and delta as well as selectivity for RasGRP compared with PKCalpha (English)

1 reference

Europe PubMed Central

20 September 2017

author name string

Yongmei Pu

1

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Europe PubMed Central

20 September 2017

Nicholas A Perry

2

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Europe PubMed Central

20 September 2017

Dazhi Yang

3

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Europe PubMed Central

20 September 2017

Nancy E Lewin

4

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Europe PubMed Central

20 September 2017

Noemi Kedei

5

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Europe PubMed Central

20 September 2017

Derek C Braun

6

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Europe PubMed Central

20 September 2017

Sung Hee Choi

7

1 reference

Europe PubMed Central

20 September 2017

Peter M Blumberg

8

1 reference

Europe PubMed Central

20 September 2017

Susan H Garfield

9

1 reference

Europe PubMed Central

20 September 2017

James C Stone

10

1 reference

Europe PubMed Central

20 September 2017

Dehui Duan

11

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20 September 2017

Victor E Marquez

12

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20 September 2017

language of work or name

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publication date

27 May 2005

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20 September 2017

Journal of Biological Chemistry

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20 September 2017

280

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20 September 2017

27329-27338

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Europe PubMed Central

20 September 2017

29

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Europe PubMed Central

20 September 2017

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Protein kinase C isozymes as potential targets for anticancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Protein kinase D: an intracellular traffic regulator on the move

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Regulation of cell apoptosis by protein kinase c delta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Conformationally constrained analogues of diacylglycerol. 21. A solid-phase method of synthesis of diacylglycerol lactones as a prelude to a combinatorial approach for the synthesis of protein kinase C isozyme-specific ligands

1 reference

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21 January 2018

Indolactam and benzolactam compounds as new medicinal leads with binding selectivity for C1 domains of protein kinase C isozymes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Non-equivalent roles for the first and second zinc fingers of protein kinase Cdelta. Effect of their mutation on phorbol ester-induced translocation in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Iridals are a novel class of ligands for phorbol ester receptors with modest selectivity for the RasGRP receptor subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s

1 reference

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21 January 2018

Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Contribution of the C1A and C1B Domains to the Membrane Interaction of Protein Kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414132200

21 January 2018

Mode of action of carcinogenic plant components

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21 January 2018

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M414132200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

ResearchGate publication ID

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