Selectin L (Q4042403)

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mammalian protein found in Homo sapiens

CD62 antigen-like family member L
leukocyte-endothelial cell adhesion molecule 1
TQ1
gp90-MEL
SELL
pln homing receptor
LAM-1
leukocyte surface antigen Leu-8
Leukocyte adhesion molecule 1
LECAM1
lymphocyte adhesion molecule 1
L-selectin
lymph node homing receptor

Language	Label	Description	Also known as
English	Selectin L	mammalian protein found in Homo sapiens	CD62 antigen-like family member L leukocyte-endothelial cell adhesion molecule 1 TQ1 gp90-MEL SELL pln homing receptor LAM-1 leukocyte surface antigen Leu-8 Leukocyte adhesion molecule 1 LECAM1 lymphocyte adhesion molecule 1 L-selectin lymph node homing receptor

Statements

1 reference

16 January 2019

UniProt protein ID

C-type lectin-like/link domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

Sushi/SCR/CCP superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

C-type lectin fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

1 reference

based on heuristic

inferred from protein domain or family

Sushi/SCR/CCP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

16 January 2019

UniProt protein ID

1 reference

16 January 2019

UniProt protein ID

molecular function

protease binding

determination method

1 reference

8 April 2019

Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

heparin binding

determination method

1 reference

8 April 2019

Higher-affinity oligosaccharide ligands for E-selectin

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

protein binding

determination method

1 reference

8 April 2019

Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

glycosphingolipid binding

determination method

1 reference

8 April 2019

Higher-affinity oligosaccharide ligands for E-selectin

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

cell adhesion molecule binding

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

calcium ion binding

determination method

1 reference

8 April 2019

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

oligosaccharide binding

determination method

1 reference

8 April 2019

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

plasma membrane

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

determination method

2 references

external side of plasma membrane

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

secretory granule membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

integral component of plasma membrane

determination method

3 references

8 April 2019

Structure of the gene encoding the human leukocyte adhesion molecule-1 (TQ1, Leu-8) of lymphocytes and neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

Characterization of a human homologue of the murine peripheral lymph node homing receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

biological process

response to ATP

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

determination method

3 references

8 April 2019

An activated L-selectin mutant with conserved equilibrium binding properties but enhanced ligand recognition under shear flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

regulation of immune response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

neutrophil degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

leukocyte migration

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

determination method

1 reference

8 April 2019

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

leukocyte tethering or rolling

determination method

1 reference

8 April 2019

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14151

determination method

physically interacts with

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1215923

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3707446

Gene Atlas image

PBB GE SELL 204563 at fs.png
732 × 530; 8 KB

0 references

EGF-like, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

sushi/SCR/CCP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

EGF-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

C-type lectin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

Selectin, C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14151

Identifiers

RefSeq protein ID

1 reference

8 February 2019

UniProt protein ID

1 reference

16 January 2019

UniProt protein ID

Ensembl protein ID

ENSP00000236147

1 reference

ensembl Release 95

Ensembl protein ID

ENSP00000236147

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(12 entries)

cswiki L-selektin
cywiki SELL
dewiki Lymphozyten-Selektin
enwiki L-selectin
eswiki L-selectina
fawiki ال-سلکتین
glwiki L-selectina
itwiki L-selectina
jawiki L-セレクチン
ruwiki L-селектин
ttwiki SELL
ukwiki SELL

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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