Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and dow (Q40437409)

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English	Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and dow	scientific article

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10 January 2020

Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression (English)

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10 January 2020

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Su-Jin Kim

1

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Kyle Winter

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Cuilan Nian

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Makoto Tsuneoka

4

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Christopher H S McIntosh

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6 April 2005

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Journal of Biological Chemistry

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22297-22307

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10 January 2020

Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

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21 January 2018

PI3K: downstream AKTion blocks apoptosis

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Regulation of cell death protease caspase-9 by phosphorylation

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

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21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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21 January 2018

Regulation of the FoxO family of transcription factors by phosphatidylinositol-3 kinase-activated signaling

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21 January 2018

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

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Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

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21 January 2018

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

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Aktion in the nucleus.

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The glucagon-like peptides

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Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

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21 January 2018

Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis

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21 January 2018

Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells

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21 January 2018

Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.

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21 January 2018

Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling

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21 January 2018

Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice

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Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion

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21 January 2018

Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes

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21 January 2018

Insulin sensitivity of muscle capillary recruitment in vivo

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21 January 2018

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

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21 January 2018

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

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21 January 2018

Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic

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21 January 2018

Parallel regulation of mitogen-activated protein kinase kinase 3 (MKK3) and MKK6 in Gq-signaling cascade

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21 January 2018

p150(Glued), Dynein, and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs

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21 January 2018

Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

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21 January 2018

Formation of noncanonical high molecular weight caspase-3 and -6 complexes and activation of caspase-12 during serum starvation induced apoptosis in AKR-2B mouse fibroblasts

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21 January 2018

Caspase-9 plays a marginal role in serum starvation-induced apoptosis

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21 January 2018

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

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21 January 2018

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

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21 January 2018

Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1.

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21 January 2018

Role of caspases in the regulation of apoptotic pancreatic islet beta-cells death.

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21 January 2018

The Bcl-2 protein family: arbiters of cell survival

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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21 January 2018

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