CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells. (Q40439589)

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10 January 2020

title

CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells (English)

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10 January 2020

1

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10 January 2020

Tanja N Hartmann

2

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10 January 2020

author name string

Jan A Burger

3

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10 January 2020

Aleksandra Glodek

4

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10 January 2020

Nobutaka Fujii

5

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10 January 2020

Meike Burger

6

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10 January 2020

language of work or name

English

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publication date

1 June 2005

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10 January 2020

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10 January 2020

volume

24

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10 January 2020

page(s)

4462-4471

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10 January 2020

issue

27

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208621

10 January 2020

exact match

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cites work

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The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways

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Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesis

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Subsecond induction of alpha4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions

21 January 2018

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Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas

21 January 2018

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Long-term survival in small-cell lung cancer: posttreatment characteristics in patients surviving 5 to 18+ years--an analysis of 1,714 consecutive patients.

21 January 2018

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The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow

21 January 2018

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The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases

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Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells

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Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140.

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The chemokine stromal cell-derived factor-1 alpha modulates alpha 4 beta 7 integrin-mediated lymphocyte adhesion to mucosal addressin cell adhesion molecule-1 and fibronectin

21 January 2018

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CXCR4 chemokine receptors (CD184) and alpha4beta1 integrins mediate spontaneous migration of human CD34+ progenitors and acute myeloid leukaemia cells beneath marrow stromal cells (pseudoemperipolesis).

21 January 2018

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7 January 2021

Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells.

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7 January 2021

Chemokines and the arrest of lymphocytes rolling under flow conditions.

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Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow

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7 January 2021

PYK2 is an adhesion kinase in macrophages, localized in podosomes and activated by beta(2)-integrin ligation

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7 January 2021

Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells

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7 January 2021

A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma

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7 January 2021

Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).

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7 January 2021

Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells

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7 January 2021

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7 January 2021

Chemotherapy of lung cancer

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7 January 2021

In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways

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7 January 2021

Involvement of chemokine receptors in breast cancer metastasis

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7 January 2021

Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms

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7 January 2021

Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.

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7 January 2021

Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1.

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7 January 2021

Biochemical signals and biological responses elicited by the focal adhesion kinase

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7 January 2021

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

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7 January 2021

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

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7 January 2021

The chemokine SDF-1alpha triggers a chemotactic response and induces cell polarization in human B lymphocytes.

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7 January 2021

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208621

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15806155%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 January 2020

0 references

1 reference