KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling. (Q40447179)

20 September 2017

KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling. (English)

1 reference

20 September 2017

3

Julieta Palomeque

1 reference

20 September 2017

Hongwei Jin

1

1 reference

20 September 2017

Lahouaria Hadri

2

1 reference

20 September 2017

Charlotte Morel

4

1 reference

20 September 2017

Ioannis Karakikes

5

1 reference

20 September 2017

Roger Kaprielian

6

1 reference

20 September 2017

Roger Hajjar

7

1 reference

20 September 2017

Djamel Lebeche

8

1 reference

20 September 2017

4 January 2010

1 reference

Journal of Molecular and Cellular Cardiology

20 September 2017

1 reference

20 September 2017

48

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20 September 2017

6

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20 September 2017

1169-1179

1 reference

Accessory subunit KChIP2 modulates the cardiac L-type calcium current

20 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Deleting the accessory subunit KChIP2 results in loss of I(to,f) and increased I(K,slow) that maintains normal action potential configuration.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Post-transcriptional gene silencing of KChIP2 and Navbeta1 in neonatal rat cardiac myocytes reveals a functional association between Na and Ito currents

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Molecular physiology of cardiac repolarization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

The cAMP response element binding protein modulates expression of the transient outward current: implications for cardiac memory.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Cytoplasmic signaling pathways that regulate cardiac hypertrophy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Modulation of A-type potassium channels by a family of calcium sensors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Electrophysiological remodeling in hypertrophy and heart failure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Modulation of action potential duration on myocyte hypertrophic pathways

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Regulation of Kv4.3 voltage-dependent gating kinetics by KChIP2 isoforms.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Regulation of transient outward current in human atrial myocytes by protein tyrosine kinase pathway

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

NFATc3-dependent loss of I(to) gradient across the left ventricular wall during chronic beta adrenergic stimulation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Mitogen-activated protein kinases control cardiac KChIP2 gene expression

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

ERK/MAPK regulates the Kv4.2 potassium channel by direct phosphorylation of the pore-forming subunit.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Novel KChIP2 isoforms increase functional diversity of transient outward potassium currents

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Concordant expression of KChIP2 mRNA, protein and transient outward current throughout the canine ventricle

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Cardiac function and electrical remodeling of the calcineurin-overexpressed transgenic mouse

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Inhibition of calcineurin and sarcolemmal Ca2+ influx protects cardiac morphology and ventricular function in K(v)4.2N transgenic mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Electrical remodeling in pressure-overload cardiac hypertrophy: role of calcineurin

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Independent regulation of cardiac Kv4.3 potassium channel expression by angiotensin II and phenylephrine

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Potassium channel down-regulation in heart failure

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Diminished transient outward currents in rat hypertrophied ventricular myocytes.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866822

Differential expression of voltage-gated K+ channel genes in left ventricular remodeled myocardium after experimental myocardial infarction

20 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Relationship between K+ channel down-regulation and [Ca2+]i in rat ventricular myocytes following myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

KChIP2 modulates the cell surface expression of Kv 1.5-encoded K(+) channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

7 January 2021

When the KChIPs are down

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

In vivo cardiac gene transfer of Kv4.3 abrogates the hypertrophic response in rats after aortic stenosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Targeted expression of a dominant-negative K(v)4.2 K(+) channel subunit in the mouse heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Cellular mechanisms of altered contractility in the hypertrophied heart: big hearts, big sparks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Reduced transient outward K+ current and cardiac hypertrophy: causal relationship or epiphenomenon?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Functional consequences of elimination of i(to,f) and i(to,s): early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1.4 and expressing a dominant-negative Kv4 alpha subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2009.12.019

10.1016/J.YJMCC.2009.12.019

7 January 2021

Identifiers

DOI

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

20051248

1 reference