Selective uncoupling of G alpha 12 from Rho-mediated signaling. (Q40450914)

20 September 2017

title

Selective uncoupling of G alpha 12 from Rho-mediated signaling. (English)

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20 September 2017

Thomas E Meigs

1

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20 September 2017

Juhi Juneja

2

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20 September 2017

C Todd DeMarco

3

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20 September 2017

Laura N Stemmle

4

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20 September 2017

Daniel D Kaplan

5

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20 September 2017

Patrick J Casey

6

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20 September 2017

language of work or name

English

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publication date

3 March 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

18

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20 September 2017

page(s)

18049-18055

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G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

20 September 2017

cites work

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Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.

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The G12 coupled thrombin receptor stimulates mitogenesis through the Shc SH2 domain.

21 January 2018

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A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

21 January 2018

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The alpha-subunit of the heterotrimeric G protein G13 activates a phospholipase D isozyme by a pathway requiring Rho family GTPases

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Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.

21 January 2018

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Conformational activation of radixin by G13 protein alpha subunit

21 January 2018

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Zonula occludens-1 is a scaffolding protein for signaling molecules. Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in epithelial cells

21 January 2018

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The transforming activity of activated G alpha 12.

21 January 2018

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A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

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Gα12 and Gα13 as key regulatory mediator in signal transduction

21 January 2018

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Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

21 January 2018

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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

21 January 2018

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Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

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Distinct regions of the cadherin cytoplasmic domain are essential for functional interaction with Galpha 12 and beta-catenin

21 January 2018

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p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

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Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release

21 January 2018

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Visualization of a functional Galpha q-green fluorescent protein fusion in living cells. Association with the plasma membrane is disrupted by mutational activation and by elimination of palmitoylation sites, but not be activation mediated by recepto

21 January 2018

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beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

21 January 2018

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Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

21 January 2018

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Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.

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Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

21 January 2018

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N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo

21 January 2018

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The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

21 January 2018

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G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription.

21 January 2018

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Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

21 January 2018

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Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

21 January 2018

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A rho exchange factor mediates thrombin and Galpha(12)-induced cytoskeletal responses

21 January 2018

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Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

21 January 2018

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Activation of Jun Kinase/Stress-activated Protein Kinase by GTPase-deficient Mutants of Gα12 and Gα13

21 January 2018

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Critical role of lysine 204 in switch I region of Galpha13 for regulation of p115RhoGEF and leukemia-associated RhoGEF.

21 January 2018

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Emerging roles for RGS proteins in cell signalling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M500445200

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20 September 2017

1 reference