Cancer gene therapy: principles, problems, and perspectives. (Q40456064)

20 September 2017

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title

Cancer gene therapy: principles, problems, and perspectives. (English)

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20 September 2017

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F Herrmann

1

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20 September 2017

publication date

1 April 1995

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Journal of Molecular Medicine

20 September 2017

published in

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20 September 2017

volume

73

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20 September 2017

issue

4

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20 September 2017

page(s)

157-163

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Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

20 September 2017

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Gene therapy for cancer

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Antibody-mediated binding of a murine ecotropic Moloney retroviral vector to human cells allows internalization but not the establishment of the proviral state.

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Interleukin 7 induces CD4+ T cell-dependent tumor rejection

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A review of gene transfer techniques

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A first step in the development of gene therapy for colorectal carcinoma: cloning, sequencing, and expression of Escherichia coli cytosine deaminase.

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Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo

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Gene transfer into mammalian somatic cells in vivo

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Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes.

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In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

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Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors

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Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction

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Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer

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Altering the genome by homologous recombination

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Exogenous expression of mouse interferon gamma cDNA in mouse neuroblastoma C1300 cells results in reduced tumorigenicity by augmented anti-tumor immunity

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A versatile and potentially general approach to the targeting of specific cell types by retroviruses: application to the infection of human cells by means of major histocompatibility complex class I and class II antigens by mouse ecotropic murine le

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Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity

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Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors

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Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

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Effects of murine tumor class I major histocompatibility complex expression on antitumor activity of tumor-infiltrating lymphocytes

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Expression of high-affinity interleukin 4 receptors on murine sarcoma cells and receptor-mediated cytotoxicity of tumor cells to chimeric protein between interleukin 4 and Pseudomonas exotoxin

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An adenovirus vector for gene transfer into neurons and glia in the brain

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Herpesviruses: expression of genes in postmitotic brain cells

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Cytokine secretion by genetically modified nonimmunogenic murine fibrosarcoma. Tumor inhibition by IL-2 but not tumor necrosis factor

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12 December 2020

Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4.

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Herpes simplex virus-mediated human hypoxanthine-guanine phosphoribosyltransferase gene transfer into neuronal cells

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Human renal carcinoma line transfected with interleukin-2 and/or interferon alpha gene(s): implications for live cancer vaccines

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Interleukin 7 generates antitumor cytotoxic T lymphocytes against murine sarcomas with efficacy in cellular adoptive immunotherapy

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Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

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12 December 2020

Induction of antitumor immunity by interleukin-2 gene-transduced mouse mammary tumor cells versus transduced mammary stromal fibroblasts

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Chemical modification of an ecotropic murine leukemia virus results in redirection of its target cell specificity

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12 December 2020

Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting

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12 December 2020

Regression of bladder tumors in mice treated with interleukin 2 gene-modified tumor cells

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12 December 2020

Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon gamma

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12 December 2020

In vitro and in vivo targeting of gene expression to melanoma cells

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Liposomes: realizing their promise

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Recent advances in retrovirus vector technology.

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Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

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Gene-marking to trace origin of relapse after autologous bone-marrow transplantation

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Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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12 December 2020

Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses

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In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

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12 December 2020

Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells

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Murine interleukin-4 displays potent anti-tumor activity in vivo

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12 December 2020

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

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12 December 2020

Transfer and expression of the human multiple drug resistance gene into live mice

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12 December 2020

Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity

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12 December 2020

Identifiers

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