Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac. (Q40458471)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15710402%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac (English)

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8 January 2020

3

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8 January 2020

Rodolphe Fischmeister

5

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8 January 2020

author name string

Sylvain Robert

1

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8 January 2020

Marjorie Maillet

2

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8 January 2020

Jean-Marie Launay

4

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8 January 2020

Luc Mercken

6

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8 January 2020

Frank Lezoualc'h

7

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8 January 2020

language of work or name

English

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publication date

1 February 2005

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8 January 2020

number of pages

7

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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8 January 2020

volume

579

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8 January 2020

page(s)

1136-1142

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8 January 2020

issue

5

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Regulation of APP cleavage by alpha-, beta- and gamma-secretases

8 January 2020

cites work

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TACE and other ADAM proteases as targets for drug discovery

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Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.

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5-HT4 receptor ligands: applications and new prospects

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Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

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A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

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Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Galphas- and Galphai/o-proteins

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Rho GTPases and the actin cytoskeleton

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A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

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Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation

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Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß 42 by Inhibiting Rho

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Effect of cell density on intracellular levels of the Alzheimer's amyloid precursor protein

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Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

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