Zonation of metabolism and gene expression in liver. (Q40459673)

20 September 2017

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title

Zonation of metabolism and gene expression in liver. (English)

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20 September 2017

K Jungermann

1

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20 September 2017

1 February 1995

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Histochemistry and Cell Biology

20 September 2017

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20 September 2017

103

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20 September 2017

2

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20 September 2017

81-91

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https://scigraph.springernature.com/pub.10.1007/bf01454004

20 September 2017

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12 December 2020

Functional Hepatocellular Heterogeneity for the Production of Plasma Proteins

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12 December 2020

Pericentral expression pattern of glucokinase mRNA in the rat liver lobulus

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12 December 2020

Functional hepatocellular heterogeneity.

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12 December 2020

Metabolic zoning of the human liver parenchyma in comparison with various mammals

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12 December 2020

Heterogeneous reciprocal localization of fructose-1,6-bis-phosphatase and of glucokinase in microdissected periportal and perivenous rat liver tissue

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12 December 2020

Biologically active products of stimulated liver macrophages (Kupffer cells).

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12 December 2020

The distribution of glucose-6-phosphatase in the liver and kidney of the mouse

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12 December 2020

Demonstration by in situ hybridization of the zonal modulation of rat liver cytochrome P-450b and P-450e gene expression after phenobarbital

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12 December 2020

Signal propagation via gap junctions, a key step in the regulation of liver metabolism by the sympathetic hepatic nerves

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12 December 2020

Hepatocyte heterogeneity in response to extracellular ATP

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12 December 2020

Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice

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12 December 2020

Immunocytochemical localization of glucocorticoid receptor in target cells.

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12 December 2020

Inhibition of glucose production during hepatic nerve stimulation in regenerating rat liver perfused in situ. Possible involvement of gap junctions in the action of sympathetic nerves.

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12 December 2020

The pattern of glycogen distribution in the liver.

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12 December 2020

Predominant localization of phosphoenolpyruvate carboxykinase mRNA in the periportal zone of rat liver parenchyma demonstrated by in situ hybridization.

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12 December 2020

Autoregulatory shift from fructolysis to lactate gluconeogenisis in rat hepatocyte suspensions. The problem of metabolic zonation of liver parenchyma

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12 December 2020

Integration of function in the hepatic acinus: intercellular communication in neural and humoral control of liver metabolism.

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12 December 2020

Modulation of the Glucagon-Dependent Induction of Phosphoenolpyruvate Carboxykinase and Tyrosine Aminotransferase by Arterial and Venous Oxygen Concentrations in Hepatocyte Cultures

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12 December 2020

Hepatocyte Heterogeneity in the Metabolism of Carbohydrates

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12 December 2020

Modulation of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene by oxygen in rat hepatocyte cultures. Evidence for a heme protein as oxygen sensor

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12 December 2020

Functional implications of liver cell heterogeneity.

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12 December 2020

Modulation by oxygen of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures

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12 December 2020

Hepatocyte heterogeneity in bile formation and hepatobiliary transport of drugs

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12 December 2020

Extracellular matrix gradients in the space of Disse: relevance to liver biology

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12 December 2020

The circadian rhythm of intra-acinar profiles of alcohol dehydrogenase activity in rat liver: a microquantitative study

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12 December 2020

Nervous control of liver metabolism and hemodynamics

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12 December 2020

Observations on the pathophysiology of liver structure

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12 December 2020

Dynamics of liver glycogen: the topochemistry of glycogen synthesis, glycogen content and glycogenolysis under the experimental conditions of glycogen accumulation and depletion

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12 December 2020

Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein

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12 December 2020

Reciprocal distribution of hexokinase and glucokinase in the periportal and perivenous zone of the rat liver acinus.

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12 December 2020

Metabolic heterogeneity of liver parenchymal cells

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12 December 2020

Zonal Liver Cell Heterogeneity

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12 December 2020

Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene

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12 December 2020

Predominant periportal expression of the phosphoenolpyruvate carboxykinase and tyrosine aminotransferase genes in rat liver. Dynamics during the daily feeding rhythm and starvation-refeeding cycle demonstrated by in situ hybridization

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12 December 2020

Localization of cells producing erythropoietin in murine liver by in situ hybridization

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12 December 2020

Histochemical distribution pattern of respiratory enzymes in the liver lobule

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12 December 2020

Regulatory elements of the erythropoietin gene.

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12 December 2020

Long-term effects of physiological oxygen concentrations on glycolysis and gluconeogenesis in hepatocyte cultures.

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12 December 2020

Differential effects of human anaphylatoxin C3a on glucose output and flow in rat liver during orthograde and retrograde perfusion: the periportal scavenger cell hypothesis

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12 December 2020

Hexokinase and glucokinase distribution in the liver lobule

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12 December 2020

Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes

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12 December 2020

Sublobular compartmentation of pharmacologic events (SCOPE): metabolic fluxes in periportal and pericentral regions of the liver lobule

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12 December 2020

Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.

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12 December 2020

Distribution of glutamine synthetase and carbamoyl-phosphate synthetase I in vertebrate liver

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12 December 2020

Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression

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12 December 2020

Methods for the study of liver cell heterogeneity

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12 December 2020

Predominant periportal expression of the phosphoenolpyruvate carboxykinase gene in liver of fed and fasted mice, hamsters and rats studied by in situ hybridization.

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12 December 2020

Positional and developmental regulation of glutamine synthetase expression in mouse liver

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12 December 2020

Detection of mRNAs present at low concentrations in rat liver by in situ hybridization: application to the study of metabolic regulation and azo dye hepatocarcinogenesis

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12 December 2020

Induction in primary culture of 'gluconeogenic' and 'glycolytic' hepatocytes resembling periportal and perivenous cells

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12 December 2020

Hepatocyte Heterogeneity in the Metabolism of Amino Acids and Ammonia

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12 December 2020

Alteration with dietary state of the activity and zonal distribution of adenylate cyclase stimulated by glucagon, fluoride and forskolin in microdissected rat liver tissue.

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12 December 2020

Expression of multidrug resistance genes in rat liver during regeneration and after carbon tetrachloride intoxication.

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12 December 2020

Distribution of cyclic AMP phosphodiesterase in microdissected periportal and perivenous rat liver tissue with different dietary states

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12 December 2020

Histochemical and immunohistochemical localization of hexokinase isoenzymes in normal rat liver

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12 December 2020

Liver fibrosis: perspectives in pathobiochemical research and clinical outlook

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12 December 2020

Zonal expression of the glucokinase gene in rat liver. Dynamics during the daily feeding rhythm and starvation-refeeding cycle demonstrated by in situ hybridization

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12 December 2020

A ferro-heme protein senses oxygen levels, which modulate the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures

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12 December 2020

Glycogen synthesis via the indirect gluconeogenic pathway in the periportal and via the direct glucose utilizing pathway in the perivenous zone of perfused rat liver

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12 December 2020

Functional heterogeneity of rat liver parenchyma and of isolated hepatocytes

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12 December 2020

Liver Cell Heterogeneity: Functions of Non-Parenchymal Cells

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12 December 2020

Heterogeneous distribution of glucose-6-phosphatase in microdissected periportal and perivenous rat liver tissue

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12 December 2020

Intrasplenic transplantation of isolated periportal and perivenous hepatocytes as a long-term system for study of liver-specific gene expression

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12 December 2020

The intra-acinar distribution patterns of alcohol-dehydrogenase activity in the liver of juvenile, castrated and testosterone-treated rats

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12 December 2020

Distribution of pyruvate kinase type L and M2 in microdissected periportal and perivenous rat liver tissue with different dietary states

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12 December 2020

Heterogeneous expression of glutamine synthetase mRNA in rat liver parenchyma revealed by in situ hybridization and Northern blot analysis of RNA from periportal and perivenous hepatocytes

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12 December 2020

Hepatocyte heterogeneity: the coming of age from the description of a biological curiosity to a partial understanding of its physiological meaning and regulation

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12 December 2020

Cell heterogeneity within the hepatic lobule of the rat: staining reactions

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12 December 2020

Immunohistochemical localization of carbamoyl-phosphate synthetase (ammonia) in adult rat liver; evidence for a heterogeneous distribution

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12 December 2020

Mechanism of the inhibition by insulin of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. Action on gene transcription, mRNA level and -stability as well as hysteresis effect

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12 December 2020

Hepatocyte heterogeneity in the metabolism of fatty acids: discrepancies on zonation of acetyl-CoA carboxylase

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12 December 2020

Changes in distribution of enzymes within the liver lobule during adaptive increases.

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12 December 2020

Hepatocyte heterogeneity and liver function

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12 December 2020

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

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12 December 2020

Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver.

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12 December 2020

Complementary distribution of carbamoylphosphate synthetase (ammonia) and glutamine synthetase in rat liver acinus is regulated at a pretranslational level

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12 December 2020

Hepatocyte heterogeneity in response to icosanoids. The perivenous scavenger cell hypothesis

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12 December 2020

Heterogeneous (positional) expression of hepatic glutamine synthetase: features, regulation and implications for hepatocarcinogenesis

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12 December 2020

Diurnal variation of the serine dehydratase mRNA level in rat liver

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12 December 2020

Heterogeneous distribution of phosphoenolpyruvate carboxykinase in rat liver parenchyma, isolated, and cultured hepatocytes

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12 December 2020

Liver cell heterogeneity. The distribution of pyruvate kinase and phosphoenolpyruvate carboxykinase (GTP) in the liver lobule of fed and starved rats

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12 December 2020

The compartmentation of glycolytic and gluconeogenic enzymes in rat kidney and liver and its significance to renal and hepatic metabolism

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12 December 2020

Zonation of glucokinase in rat liver changes during postnatal development

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12 December 2020

Identifiers

DOI

10.1007/BF01454004

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20 September 2017

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PubMed ID

7634156