A high-throughput screen to identify inhibitors of amyloid beta-protein precursor processing. (Q40461412)

20 September 2017

A high-throughput screen to identify inhibitors of amyloid beta-protein precursor processing. (English)

1 reference

20 September 2017

Pancham Bakshi

1

1 reference

20 September 2017

Yung-Feng Liao

2

1 reference

20 September 2017

Jun Gao

3

1 reference

20 September 2017

Jake Ni

4

1 reference

20 September 2017

Ross Stein

5

1 reference

20 September 2017

Li-An Yeh

6

1 reference

20 September 2017

Michael S Wolfe

7

1 reference

20 September 2017

1 February 2005

1 reference

Journal of Biomolecular Screening

20 September 2017

1 reference

20 September 2017

10

1 reference

20 September 2017

1

1 reference

20 September 2017

1-12

1 reference

Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum

20 September 2017

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Amyloid, the presenilins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

The C-terminus of the beta protein is critical in amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Therapeutic strategies for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

BACE1: the beta-secretase enzyme in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Difluoro ketone peptidomimetics suggest a large S1 pocket for Alzheimer's gamma-secretase: implications for inhibitor design

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Control of expression of the Tn10-encoded tetracycline resistance genes. Equilibrium and kinetic investigation of the regulatory reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057104270068

21 January 2018

Identifiers

DOI

10.1177/1087057104270068

1 reference

20 September 2017

1 reference