PKC-alpha-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells. (Q40469512)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15657300%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

PKC-alpha-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells (English)

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7 January 2020

0 references

1

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7 January 2020

Philip Poronnik

series ordinal

3

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7 January 2020

author name string

Carol A Pollock

series ordinal

2

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7 January 2020

publication date

18 January 2005

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American Journal of Physiology - Renal Physiology

7 January 2020

published in

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7 January 2020

volume

288

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7 January 2020

issue

6

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7 January 2020

page(s)

F1227-35

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Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells

7 January 2020

cites work

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Dopamine acutely decreases apical membrane Na/H exchanger NHE3 protein in mouse renal proximal tubule

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Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells

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Protein Kinase Cα-Induced p115RhoGEF Phosphorylation Signals Endothelial Cytoskeletal Rearrangement

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Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells

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Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.

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Dopamine acutely stimulates Na+/H+ exchanger (NHE3) endocytosis via clathrin-coated vesicles: dependence on protein kinase A-mediated NHE3 phosphorylation

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Effects of pathophysiological concentrations of albumin on NHE3 activity and cell proliferation in primary cultures of human proximal tubule cells

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Lysophosphatidic acid stimulates brush border Na+/H+ exchanger 3 (NHE3) activity by increasing its exocytosis by an NHE3 kinase A regulatory protein-dependent mechanism

21 January 2018

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Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes

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The Adaptor Protein ARH Escorts Megalin to and through Endosomes

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