Polyamine catabolism is enhanced after traumatic brain injury. (Q40473351)

20 September 2017

Polyamine catabolism is enhanced after traumatic brain injury. (English)

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20 September 2017

traumatic brain injury

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author

Tracy Murray-Stewart

4

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20 September 2017

Kamyar Zahedi

1

1 reference

20 September 2017

Francis Huttinger

2

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20 September 2017

Ryan Morrison

3

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20 September 2017

Robert A Casero

5

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20 September 2017

Kenneth I Strauss

6

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20 September 2017

1 March 2010

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20 September 2017

Journal of Neurotrauma

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20 September 2017

27

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20 September 2017

3

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20 September 2017

515-525

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Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging

20 September 2017

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Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences

22 September 2017

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Epidemiology and prevention of head injuries: literature review

22 September 2017

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Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia

22 September 2017

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The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line

22 September 2017

1 reference

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Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine

22 September 2017

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Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines

22 September 2017

1 reference

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Polyamine and aminoguanidine treatments to promote structural and functional recovery in the adult mammalian brain after injury: a brief literature review and preliminary data about their combined administration

22 September 2017

1 reference

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Epidemiology of traumatic brain injury and subarachnoid hemorrhage

22 September 2017

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Traumatic brain injury: a review

22 September 2017

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Cyclooxygenase-2-specific inhibitor improves functional outcomes, provides neuroprotection, and reduces inflammation in a rat model of traumatic brain injury

22 September 2017

1 reference

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Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury

22 September 2017

1 reference

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Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury

22 September 2017

1 reference

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Spermidine/spermine N1-acetyl transferase activity in rat brain following transient focal cerebral ischemia and reperfusion

22 September 2017

1 reference

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Anaerobic and aerobic pathways for salvage of proximal tubules from hypoxia-induced mitochondrial injury

22 September 2017

1 reference

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Oxidation of polyamines and brain injury

22 September 2017

1 reference

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Polyamines: mysterious modulators of cellular functions

22 September 2017

1 reference

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Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates

22 September 2017

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Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response

22 September 2017

1 reference

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Polyamines, DNA methylation and cell differentiation.

22 September 2017

1 reference

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George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury

22 September 2017

1 reference

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Polyamines in neurotrauma. Ubiquitous molecules in search of a function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Polyamine metabolism in different pathological states of the brain

22 September 2017

1 reference

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Antioxidative and metal-chelating effects of polyamines.

22 September 2017

1 reference

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Ornithine decarboxylase activity in in vivo and in vitro models of cerebral ischemia

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Spermine inhibition of monocyte activation and inflammation.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Hydrogen peroxide enhances signal-responsive arachidonic acid release from neurons: role of mitogen-activated protein kinase.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Polyamines and NMDA receptors modulate pericapillary astrocyte swelling following cerebral cryo-injury in the rat.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Polyamine reutilization and turnover in brain.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Allosteric activation of brain mitochondrial Ca2+ uptake by spermine and by Ca2+: developmental changes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Blood-brain barrier breakdown in cold-injured brain is linked to a biphasic stimulation of ornithine decarboxylase activity and polyamine synthesis: both are coordinately inhibited by verapamil, dexamethasone, and aspirin.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Evidence for a role of neosynthetized putrescine in the increase of glial fibrillary acidic protein immunoreactivity induced by a mechanical lesion in the rat brain.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Polyamine uptake, binding and release in rat brain

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Spermine: an anti-oxidant and anti-inflammatory agent.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Endothelium-Dependent Responses After Experimental Brain Injury

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

[Physiological functions of polyamines and regulation of polyamine content in cells].

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Oxidative metabolites are involved in polyamine-induced microglial cell death

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Effect of difluoromethylornithine on reperfusion injury after temporary middle cerebral artery occlusion

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Neuroprotective effects of spermine following hypoxic-ischemic-induced brain damage: a mechanistic study

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Polyamines and central nervous system injury: spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Regulation of SSAT expression by synaptic activity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

The polyamine stress response: tissue-, endocrine-, and developmental-dependent regulation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats.

20 August 2018

1 reference

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Contribution of polyamine oxidase to brain injury after trauma.

20 August 2018

1 reference

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Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Increased ornithine decarboxylase activity and protein level in the cortex following traumatic brain injury in rats.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Cerebral penetration injury leads to H2O2 generation in microdialysis samples.

20 August 2018

1 reference

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Effect of difluoromethylornithine treatment on regional ornithine decarboxylase activity and edema formation after experimental brain injury.

20 August 2018

1 reference

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Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry.

20 August 2018

1 reference

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Accumulation of exogenous polyamines in gerbil brain after ischemia.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Difluoromethylornithine decreases postischemic brain edema and blood-brain barrier breakdown.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867553

Free radical scavenging action of the natural polyamine spermine in rat liver mitochondria

20 August 2018

1 reference

12 December 2020

Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue

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12 December 2020

Glucocorticoid regulation of spermidine acetylation in the rat brain

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12 December 2020

Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis

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12 December 2020

Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage

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12 December 2020

Modulation of N-methyl-d-aspartate receptors by hydroxyl radicals in rat cortical neurons in vitro

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12 December 2020

Polyamine induced Z-conformation of native calf thymus DNA

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12 December 2020

Rapid high-performance liquid chromatographic method for the quantitation of polyamines as their dansyl derivatives: application to plant and animal tissues

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12 December 2020

Role of polyamines in myocardial ischemia/reperfusion injury and their interactions with nitric oxide

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12 December 2020

Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury

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12 December 2020

Overexpression of spermidine/spermine N-acetyltransferase in transgenic mice protects the animals from kainate-induced toxicity

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12 December 2020

The contribution of endogenous polyamines to the permeability transition of rat liver mitochondria

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12 December 2020

Identifiers

DOI

10.1089/NEU.2009.1097

1 reference

20 September 2017

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20 September 2017

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