Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells (Q40486229)

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English	Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells	scientific article

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scholarly article

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Europe PubMed Central

20 September 2017

Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells (English)

1 reference

Europe PubMed Central

20 September 2017

3

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Europe PubMed Central

20 September 2017

Douglas A. Lauffenburger

5

object named as

Douglas A Lauffenburger

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Europe PubMed Central

20 September 2017

4

object named as

H Steven Wiley

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Europe PubMed Central

20 September 2017

author name string

Bart S Hendriks

1

1 reference

Europe PubMed Central

20 September 2017

Gayla Orr

2

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Europe PubMed Central

20 September 2017

language of work or name

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publication date

29 November 2004

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Europe PubMed Central

20 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

20 September 2017

280

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Europe PubMed Central

20 September 2017

6157-6169

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Europe PubMed Central

20 September 2017

7

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Europe PubMed Central

20 September 2017

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Untangling the ErbB signalling network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

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Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

HER2-Mediated Effects on EGFR Endosomal Sorting: Analysis of Biophysical Mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

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Alternative intracellular routing of ErbB receptors may determine signaling potency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

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The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

1 reference

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21 January 2018

Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects

1 reference

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Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

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Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

1 reference

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Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.

1 reference

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21 January 2018

Quantitative relationship among integrin-ligand binding, adhesion, and signaling via focal adhesion kinase and extracellular signal-regulated kinase 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Mathematical models of protein kinase signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

MAP kinase cascade signaling and endocytic trafficking: a marriage of convenience?

1 reference

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21 January 2018

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

1 reference

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21 January 2018

Computational modeling of the EGF-receptor system: a paradigm for systems biology

1 reference

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21 January 2018

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410491200

21 January 2018

Engineering epidermal growth factor for enhanced mitogenic potency

1 reference

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21 January 2018

Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M410491200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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