Generation of a synthetic lymphoid tissue-like organoid in mice (Q40487229)

21 September 2017

Generation of a synthetic lymphoid tissue-like organoid in mice (English)

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21 September 2017

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Sachiko Suematsu

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PubMed ID

15568019

21 September 2017

Takeshi Watanabe

series ordinal

2

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21 September 2017

28 November 2004

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21 September 2017

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21 September 2017

22

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21 September 2017

12

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21 September 2017

1539-1545

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https://scigraph.springernature.com/pub.10.1038/nbt1039

21 September 2017

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cites work

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Inflammation, a prototype for organogenesis of the lymphopoietic/hematopoietic system

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Organogenesis of lymphoid tissues

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Chemokines in lymphopoiesis and lymphoid organ development

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Chemokines and cell migration in secondary lymphoid organs

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Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin

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Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice

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The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues.

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7 January 2021

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs

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7 January 2021

Lymph node genesis is induced by signaling through the lymphotoxin beta receptor.

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7 January 2021

Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells

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Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen

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Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

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Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization

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7 January 2021

The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes

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7 January 2021

Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation

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A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes

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Chemokine requirements for B cell entry to lymph nodes and Peyer's patches.

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The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment

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Cutting edge: the B cell chemokine CXC chemokine ligand 13/B lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules

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Chronic inflammation caused by lymphotoxin is lymphoid neogenesis

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Cutting edge: ectopic expression of the chemokine TCA4/SLC is sufficient to trigger lymphoid neogenesis.

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7 January 2021

Ectopic expression of the murine chemokines CCL21a and CCL21b induces the formation of lymph node-like structures in pancreas, but not skin, of transgenic mice

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BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

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Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.

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7 January 2021

Ectopic LTαβ Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted Sulfotransferase

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Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue

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Selective elimination of double-positive immature thymocytes by a thymic epithelial cell line

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Dendritic cells and the control of immunity

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7 January 2021

Antigen presentation and T cell stimulation by dendritic cells

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7 January 2021

Tolerogenic dendritic cells

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7 January 2021

Efficient selection for high-expression transfectants with a novel eukaryotic vector

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7 January 2021

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

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7 January 2021

Identifiers

DOI

10.1038/NBT1039

1 reference

21 September 2017

1 reference

PubMed ID

15568019