Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism (Q40488094)

21 September 2017

Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism (English)

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21 September 2017

Sunil Chada

1

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21 September 2017

Abner M Mhashilkar

2

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21 September 2017

Rajagopal Ramesh

3

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21 September 2017

John B Mumm

4

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21 September 2017

R Bryan Sutton

5

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21 September 2017

Dora Bocangel

6

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21 September 2017

Mingzhong Zheng

7

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21 September 2017

Elizabeth A Grimm

8

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21 September 2017

Suhendan Ekmekcioglu

9

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21 September 2017

1 December 2004

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21 September 2017

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21 September 2017

10

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21 September 2017

6

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21 September 2017

1085-1095

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MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.

21 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

The MUC gene family: their role in diagnosis and early detection of pancreatic cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Combination therapy of Ad-mda7 and trastuzumab increases cell death in Her-2/neu-overexpressing breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Interleukin 20: discovery, receptor identification, and role in epidermal function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

The melanoma differentiation associated gene mda-7 suppresses cancer cell growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Loss of MDA-7 expression with progression of melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Cutting edge: immune cells as sources and targets of the IL-10 family members?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Tumor suppressor MDA-7/IL-24 selectively inhibits vascular smooth muscle cell growth and migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.08.020

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMTHE.2004.08.020

1 reference

21 September 2017

1 reference