BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways (Q40498143)

21 September 2017

BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways (English)

1 reference

21 September 2017

3

1 reference

21 September 2017

Nicholas W Morrell

4

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author name string

Trina K Jeffery

series ordinal

1

1 reference

PubMed ID

15516492

21 September 2017

Paul D Upton

series ordinal

2

1 reference

21 September 2017

29 October 2004

1 reference

American Journal of Physiology - Lung Cellular and Molecular Physiology

21 September 2017

1 reference

21 September 2017

288

1 reference

21 September 2017

2

1 reference

21 September 2017

L370-8

1 reference

Vascular smooth muscle cells express multiple type I receptors for TGF-beta, activin, and bone morphogenetic proteins.

21 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via the proteolytically activated receptor-1 and a protein kinase C-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

p27(Kip1) is important in modulating pulmonary artery smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

alpha-smooth-muscle actin and microvascular precursor smooth-muscle cells in pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Protein kinase C-independent activation of protein kinase D is involved in BMP-2-induced activation of stress mitogen-activated protein kinases JNK and p38 and osteoblastic cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Alpha smooth muscle actin expression in developing and adult human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Role of Smad1 and Smad4 proteins in the induction of p21WAF1,Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

The ever-increasing complexity of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

The ultrastructure of plexogenic pulmonary arteriopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Cellular and molecular mechanisms of pulmonary vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Adventitial fibroblasts: defining a role in vessel wall remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Characterization of type I receptors for transforming growth factor-beta and activin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

BMP-2 inhibits proliferation of human aortic smooth muscle cells via p21Cip1/Waf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

Distribution of obstructive intimal lesions and their cellular phenotypes in chronic pulmonary hypertension. A morphometric and immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00242.2004

10.1152/AJPLUNG.00242.2004

21 January 2018

Identifiers

DOI

1 reference

release_ycrwtcwxdjcpphsqnxsrneuy7y

21 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ycrwtcwxdjcpphsqnxsrneuy7y

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

15516492

1 reference

PubMed ID

15516492