The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner (Q40499588)

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English	The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 September 2017

The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner (English)

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Europe PubMed Central

PubMed publication ID

21 September 2017

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Lori S Hart

1

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Europe PubMed Central

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21 September 2017

Steven M Yannone

2

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Europe PubMed Central

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21 September 2017

Christine Naczki

3

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Europe PubMed Central

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21 September 2017

Joseph S Orlando

4

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21 September 2017

Stephen B Waters

5

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Europe PubMed Central

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21 September 2017

Steven A Akman

6

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21 September 2017

David J Chen

7

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21 September 2017

David Ornelles

8

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21 September 2017

Constantinos Koumenis

9

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21 September 2017

language of work or name

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publication date

26 October 2004

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21 September 2017

Journal of Biological Chemistry

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21 September 2017

280

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21 September 2017

2

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21 September 2017

1474-1481

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21 September 2017

The DNA-dependent protein kinase

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https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Deletion of the E4 region of the genome produces adenovirus DNA concatemers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Genomic instability: potential contributions to tumour and normal tissue response, and second tumours, after radiotherapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Transfer of Ku86 RNA antisense decreases the radioresistance of human fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

E4orf6 variants with separate abilities to augment adenovirus replication and direct nuclear localization of the E1B 55-kilodalton protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Replicating molecules of polyoma virus DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

DNA-dependent protein kinase defects are linked to deficiencies in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Creation and repair of specific DNA double-strand breaks in vivo following infection with adenovirus vectors expressing Saccharomyces cerevisiae HO endonuclease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Low-dose radiation: Thresholds, bystander effects, and adaptive responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Phosphorylation of histone H2AX as a measure of radiosensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Poly(ADP-ribose) polymerase-1 inhibits ATM kinase activity in DNA damage response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

End-joining of reconstituted histone H2AX-containing chromatin in vitro by soluble nuclear proteins from human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

"Hit-and-run" transformation by adenovirus oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

DNA-PKcs function regulated specifically by protein phosphatase 5

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Accessibility to topoisomerases I and II regulates the replication efficiency of simian virus 40 minichromosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409934200

21 January 2018

Identifiers

10.1074/JBC.M409934200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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