The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. (Q40506613)

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English	The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.	scientific article

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. (English)

1 reference

Europe PubMed Central

21 September 2017

phosphorylation

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Angela L. Tyner

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Angela L Tyner

6

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author name string

Andrea Haegebarth

1

1 reference

Europe PubMed Central

21 September 2017

Darien Heap

2

1 reference

Europe PubMed Central

21 September 2017

Wenjun Bie

3

1 reference

Europe PubMed Central

21 September 2017

Jason J Derry

4

1 reference

Europe PubMed Central

21 September 2017

Stéphane Richard

5

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Europe PubMed Central

21 September 2017

language of work or name

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publication date

7 October 2004

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Europe PubMed Central

21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

21 September 2017

279

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Europe PubMed Central

21 September 2017

52

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Europe PubMed Central

21 September 2017

54398-54404

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Europe PubMed Central

21 September 2017

Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

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Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Solution structure and backbone dynamics of the non-receptor protein-tyrosine kinase-6 Src homology 2 domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

STAR, a gene family involved in signal transduction and activation of RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

The identification of two Drosophila K homology domain proteins. Kep1 and SAM are members of the Sam68 family of GSG domain proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Inhibition of human immunodeficiency virus type 1 Rev function by a dominant-negative mutant of Sam68 through sequestration of unspliced RNA at perinuclear bundles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Direct participation of Sam68, the 68-kilodalton Src-associated protein in mitosis, in the CRM1-mediated Rev nuclear export pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Expression of exogenous Sam68, the 68-kilodalton SRC-associated protein in mitosis, is able to alleviate impaired Rev function in astrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

A novel function for Sam68: enhancement of HIV-1 RNA 3' end processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Signal-dependent regulation of splicing via phosphorylation of Sam68

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Salpalpha and Salpbeta, growth-arresting homologs of Sam68

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

P62 association with RNA is regulated by tyrosine phosphorylation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Neoplastic transformation and tumorigenesis associated with sam68 protein deficiency in cultured murine fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Retardation of the G2-M phase progression on gene disruption of RNA binding protein Sam68 in the DT40 cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Phosphorylation of the Src substrate Sam68 by Cdc2 during mitosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Nuclear tyrosine phosphorylation: the beginning of a map.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Regulation of cell death by the Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Death by Abl: a matter of location

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Nuclear transport and cancer: from mechanism to intervention

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409579200

21 January 2018

Identifiers

10.1074/JBC.M409579200

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

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