Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region (Q40508891)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

prion protein family

0 references

apoptotic process

0 references

François Major

11

object named as

François Major

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Bettina Drisaldi

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Janaky Coomaraswamy

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Peter Mastrangelo

3

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Bob Strome

4

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Jing Yang

5

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Joel C Watts

6

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

M Azhar Chishti

7

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Melissa Marvi

8

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Otto Windl

9

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Rosemary Ahrens

10

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Man-Sun Sy

12

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Hans Kretzschmar

13

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Paul E Fraser

14

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Howard T J Mount

15

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

David Westaway

16

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

0 references

publication date

29 September 2004

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

53

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

55443-55454

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

De novo generation of a PrPSc-like conformation in living cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Mammalian prion proteins: enigma, variation and vaccination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Scrapie prion protein contains a phosphatidylinositol glycolipid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

NMR structure of the mouse prion protein domain PrP(121-231)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Two different neurodegenerative diseases caused by proteins with similar structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion protein selectively binds copper(II) ions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

The PrP-like protein Doppel binds copper

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Doppel-induced cerebellar degeneration in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion protein protects human neurons against Bax-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion protein prevents human breast carcinoma cell line from tumor necrosis factor alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Mammalian prion biology: one century of evolving concepts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Structure and polymorphism of the mouse prion protein gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Grand ideas floating freely. Conference on the new prion biology: basic science, diagnosis and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Neurotoxicity of a prion protein fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prions prevent neuronal cell-line death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Intercellular transfer of the cellular prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

The N-terminal region of the prion protein ectodomain contains a lipid raft targeting determinant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Identification of cryptic nuclear localization signals in the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Anterograde and retrograde intracellular trafficking of fluorescent cellular prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Metal ions and prion diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Copper stimulates endocytosis of the prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Essential role of the prion protein N terminus in subcellular trafficking and half-life of cellular prion protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion and doppel proteins bind to granule cells of the cerebellum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Potential pseudoknots in the PrP-encoding mRNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Thermodynamic prediction of conserved secondary structure: application to the RRE element of HIV, the tRNA-like element of CMV and the mRNA of prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

RNA molecules stimulate prion protein conversion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Small, highly structured RNAs participate in the conversion of human recombinant PrP(Sen) to PrP(Res) in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

NMR structure of the human doppel protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Prion protein is necessary for normal synaptic function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Altered circadian activity rhythms and sleep in mice devoid of prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404794200

21 January 2018

Identifiers

10.1074/JBC.M404794200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

release_yicuz4mmxbcizo25yywlkhi5yu

1 reference

https://api.fatcat.wiki/v0/release/yicuz4mmxbcizo25yywlkhi5yu

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40508891&oldid=1972505256"