Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface (Q40519419)

21 September 2017

Identification of a novel epitope in the thyroid-stimulating hormone receptor ectodomain acting as intramolecular signaling interface (English)

1 reference

21 September 2017

Gunnar Kleinau

1

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21 September 2017

Holger Jäschke

2

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21 September 2017

Susanne Neumann

3

1 reference

21 September 2017

Jens Lättig

4

1 reference

21 September 2017

Ralf Paschke

5

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21 September 2017

Gerd Krause

6

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21 September 2017

language of work or name

English

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publication date

2 September 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

51590-51600

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21 September 2017

49

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Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Structural principles of leucine-rich repeat (LRR) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Crystal structure of human chorionic gonadotropin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Three-dimensional structure of human follicle-stimulating hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Mapping the receptor binding regions of human chorionic gonadotropin (hCG) using disulfide peptides of its beta-subunit: possible involvement of the disulfide bonds Cys(9)-Cys(57) and Cys(23)-Cys(72) in receptor binding of the hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Structural requirements for mutational lutropin/choriogonadotropin receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Activation of the luteinizing hormone receptor in the extracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: studies using chimeric human and fly receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Rescue of intracellularly trapped lutropin receptor exodomain by endodomain and reconstitution of a functional membrane receptor: interaction between exo- and endodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Requirement of cysteine residues in exons 1-6 of the extracellular domain of the luteinizing hormone receptor for gonadotropin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Thyrotropin receptor cleavage at site 1 does not involve a specific amino acid motif but instead depends on the presence of the unique, 50 amino acid insertion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Role of the carboxyl-terminal half of the extracellular domain of the human thyrotropin receptor in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

A new subclass of the luteinizing hormone/chorionic gonadotropin receptor lacking exon 10 messenger RNA in the New World monkey (Platyrrhini) lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Model of human chorionic gonadotropin and lutropin receptor interaction that explains signal transduction of the glycoprotein hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Structure of a CXC chemokine-receptor fragment in complex with interleukin-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Deletions in the third intracellular loop of the thyrotropin receptor. A new mechanism for constitutive activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Homozygous mutation within the conserved Ala-Phe-Asn-Glu-Thr motif of exon 7 of the LH receptor causes male pseudohermaphroditism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Advances in the molecular understanding of gonadotropins-receptors interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Human follicle stimulating hormone receptor trafficking and hormone binding sites in the amino terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Targeted restoration of cleavage in a noncleaving thyrotropin receptor demonstrates that cleavage is insufficient to enhance ligand-independent activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Functional assessment of the thyrotropin receptor-beta subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

The role of the hinge region of the luteinizing hormone receptor in hormone interaction and signal generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

Structure of the Nogo Receptor Ectodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404748200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404748200

1 reference

21 September 2017

1 reference