Development and refinement of pregnane X receptor (PXR) DNA binding site model using information theory: insights into PXR-mediated gene regulation. (Q40524591)

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scientific article published on 16 August 2004

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English	Development and refinement of pregnane X receptor (PXR) DNA binding site model using information theory: insights into PXR-mediated gene regulation.	scientific article published on 16 August 2004

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scholarly article

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31 December 2019

Development and refinement of pregnane X receptor (PXR) DNA binding site model using information theory: insights into PXR-mediated gene regulation (English)

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31 December 2019

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author name string

Carrie A Vyhlidal

1

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31 December 2019

J Steven Leeder

3

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16 August 2004

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31 December 2019

Journal of Biological Chemistry

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279

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45

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46779-46786

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31 December 2019

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408395200

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The RXR heterodimers and orphan receptors

1 reference

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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

1 reference

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

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Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

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Quantitative prediction of NF-kappa B DNA-protein interactions

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A Mathematical Theory of Communication

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Sequence walkers: a graphical method to display how binding proteins interact with DNA or RNA sequences

1 reference

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Information content of individual genetic sequences.

1 reference

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Theory of molecular machines. II. Energy dissipation from molecular machines.

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Using information content and base frequencies to distinguish mutations from genetic polymorphisms in splice junction recognition sites.

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Genome-wide prediction, display and refinement of binding sites with information theory-based models

1 reference

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MatchMiner: a tool for batch navigation among gene and gene product identifiers

1 reference

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21 January 2018

GoMiner: a resource for biological interpretation of genomic and proteomic data

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Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10.

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A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression

1 reference

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21 January 2018

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

1 reference

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Information content of binding sites on nucleotide sequences

1 reference

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21 January 2018

Recent advances in computational promoter analysis in understanding the transcriptional regulatory network

1 reference

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Information theory-based analysis of CYP2C19, CYP2D6 and CYP3A5 splicing mutations.

1 reference

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21 January 2018

Using sequence logos and information analysis of Lrp DNA binding sites to investigate discrepancies between natural selection and SELEX.

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21 January 2018

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

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21 January 2018

Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element

1 reference

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21 January 2018

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

1 reference

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21 January 2018

Determinants for selective RAR and TR recognition of direct repeat HREs.

1 reference

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21 January 2018

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

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21 January 2018

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

1 reference

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21 January 2018

Bioinformatic principles underlying the information content of transcription factor binding sites

1 reference

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21 January 2018

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M408395200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15316010%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15316010%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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