Processing of protein precursors by a novel family of subtilisin-related mammalian endoproteases (Q40532922)

21 September 2017

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title

Processing of protein precursors by a novel family of subtilisin-related mammalian endoproteases (English)

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21 September 2017

Smeekens SP

1

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21 September 2017

1 February 1993

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21 September 2017

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21 September 2017

11

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21 September 2017

2

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21 September 2017

182-186

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Post-translational proteolysis in polypeptide hormone biosynthesis

21 September 2017

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https://api.crossref.org/works/10.1038%2FNBT0293-182

Mammalian subtilisins: the long-sought dibasic processing endoproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Structure of a yeast pheromone gene (MF alpha): a putative alpha-factor precursor contains four tandem copies of mature alpha-factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Sequence of the preprotoxin dsRNA gene of type I killer yeast: multiple processing events produce a two-component toxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

cDNA sequence of a Drosophila melanogaster gene, Dfur1, encoding a protein structurally related to the subtilisin-like proprotein processing enzyme furin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Pro-sequence of subtilisin can guide the refolding of denatured subtilisin in an intermolecular process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Posttranslational processing of the prohormone-cleaving Kex2 protease in the Saccharomyces cerevisiae secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

The pro-region of the Kex2 endoprotease of Saccharomyces cerevisiae is removed by self-processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Characterization of PC2, a mammalian Kex2 homologue, following expression of the cDNA in microinjected Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Molecular dissection of the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Subtilisin--an enzyme designed to be engineered

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

Endopeptidases and prohormone processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Insulin biosynthesis: evidence for a precursor

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Characterization of KEX2-encoded endopeptidase from yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

cDNA and Gene Structure for a Human Subtilisin-Like Protease with Cleavage Specificity for Paired Basic Amino Acid Residues

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Intracellular targeting and structural conservation of a prohormone-processing endoprotease.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

A unique Kex2-like endoprotease from Drosophila melanogaster is expressed in the central nervous system during early embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Conservation of the prohormone convertase gene family in metazoa: analysis of cDNAs encoding a PC3-like protein from hydra

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Secretion and autoproteolytic maturation of subtilisin

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Regulation of PACE propeptide-processing activity: requirement for a post-endoplasmic reticulum compartment and autoproteolytic activation

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Homology modelling and protein engineering strategy of subtilases, the family of subtilisin-like serine proteinases

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Molecular and enzymatic properties of furin, a Kex2-like endoprotease involved in precursor cleavage at Arg-X-Lys/Arg-Arg sites.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Expression of the Saccharomyces cerevisiae Kex2p endoprotease in inset cells. Evidence for a carboxy-terminal autoprocessing event

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Peptide processing and targeting in the neuronal secretory pathway

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Circulating proalbumin associated with a variant proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Precursors for peptide hormones share common secondary structures forming features at the proteolytic processing sites

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition

1 reference

https://api.crossref.org/works/10.1038%2FNBT0293-182

7 January 2021

Identifiers

DOI

10.1038/NBT0293-182

1 reference

release_jbwkxk25d5frtlcpgrnb47zrni

21 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jbwkxk25d5frtlcpgrnb47zrni

24 November 2022

mapped directly with Wikidata item

PubMed ID

7763370

1 reference

PubMed ID

7763370