Topoisomerase II in multiple drug resistance (Q40535267)

21 September 2017

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title

Topoisomerase II in multiple drug resistance (English)

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21 September 2017

multiple drug resistance

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G A Hofmann

1

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PubMed ID

7765323

21 September 2017

M R Mattern

series ordinal

2

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21 September 2017

1 January 1993

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21 September 2017

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21 September 2017

12

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21 September 2017

1-3

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21 September 2017

137-154

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https://scigraph.springernature.com/pub.10.1007/bf00744662

21 September 2017

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cites work

Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells selected for resistance to teniposide

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12 December 2020

Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.

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12 December 2020

An overview of membrane, cytosolic and nuclear proteins associated with the expression of resistance to multiple drugs in vitro

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12 December 2020

Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells

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12 December 2020

Transient activation of topoisomerase I in leukotriene D4 signal transduction in human cells

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12 December 2020

Expressions of DNA topoisomerase I and II gene and the genes possibly related to drug resistance in human myeloma cells

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12 December 2020

Immunohistochemical Detection of P Glycoprotein, Glutathione S Transferase and DNATopoisomerase II in Human Tumors

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12 December 2020

Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases

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12 December 2020

Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II

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12 December 2020

Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

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12 December 2020

P-glycoprotein but not topoisomerase II and glutathione-S-transferase-pi accounts for enhanced intracellular drug-resistance in LoVo MDR human cell lines

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12 December 2020

Supercoils in human DNA

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12 December 2020

The measurement of nuclear topoisomerase II inhibition in vitro: a possible tool for detecting resistance on a subcellular level in haematopoietic malignancies

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12 December 2020

Structure and reactions of closed duplex DNA

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12 December 2020

Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line

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12 December 2020

DNA topoisomerase poisons as antitumor drugs

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12 December 2020

Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage

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12 December 2020

Overexpression of P-glycoprotein and alterations in topoisomerase II in P388 mouse leukemia cells selected in vivo for resistance to mitoxantrone

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12 December 2020

Potentiation of topoisomerase inhibitor-induced DNA strand breakage and cytotoxicity by tumor necrosis factor: enhancement of topoisomerase activity as a mechanism of potentiation.

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12 December 2020

Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content.

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12 December 2020

Development and cross-resistance characteristics of a subline of P388 leukemia resistant to 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

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12 December 2020

Characterization of a subline of P388 leukemia resistant to amsacrine: evidence of altered topoisomerase II function

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12 December 2020

DNA topoisomerase-targeting antitumor agents and drug resistance

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12 December 2020

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

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12 December 2020

Proliferation dependence of topoisomerase II mediated drug action

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12 December 2020

Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II.

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12 December 2020

Study of molecular markers of resistance to m-AMSA in a human breast cancer cell line. Decrease of topoisomerase II and increase of both topoisomerase I and acidic glutathione S transferase

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12 December 2020

Molecular targets in oncology: implications of the multidrug resistance gene.

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12 December 2020

Topoisomerase-targeting antitumor drugs: mechanisms of cytotoxicity and resistance

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12 December 2020

Phorbol esters induce multidrug resistance in human breast cancer cells

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12 December 2020

Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression

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12 December 2020

Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells

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12 December 2020

Expressions of resistance and cross-resistance in teniposide-resistant L1210 cells

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12 December 2020

Direct correlation between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and -resistant P388 leukemia cell lines

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12 December 2020

Lack of cross-resistance to fostriecin in a human small-cell lung carcinoma cell line showing topoisomerase II-related drug resistance.

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12 December 2020

DNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA.

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12 December 2020

Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide

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12 December 2020

Effect of the calmodulin inhibitor trifluoperazine on phosphorylation of P-glycoprotein and topoisomerase II: relationship to modulation of subcellular distribution, DNA damage and cytotoxicity of doxorubicin in multidrug resistant L1210 mouse leuke

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12 December 2020

Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26).

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12 December 2020

DNA breakage in human lung carcinoma cells and nuclei that are naturally sensitive or resistant to etoposide and teniposide

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12 December 2020

Quantitative adaptation of the bacteriophage P4 DNA unknotting assay for use in the biochemical and pharmacological characterization of topoisomerase II

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12 December 2020

Expression of several resistance mechanisms in untreated human kidney and lung carcinomas

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12 December 2020

Characterization of acquired epipodophyllotoxin resistance in a Chinese hamster ovary cell line: loss of drug-stimulated DNA cleavage activity

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12 December 2020

Purification of topoisomerase II from amsacrine-resistant P388 leukemia cells. Evidence for two forms of the enzyme

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12 December 2020

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

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12 December 2020

Attenuated topoisomerase II content directly correlates with a low level of drug resistance in a Chinese hamster ovary cell line

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12 December 2020

Combined modalities of resistance in etoposide-resistant human KB cell lines.

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12 December 2020

Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

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12 December 2020

Unknotting the complexities of multidrug resistance: the involvement of DNA topoisomerases in drug action and resistance.

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12 December 2020

Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase II activity in vitro

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12 December 2020

The role of topoisomerase II in drug resistance

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12 December 2020

Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.

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12 December 2020

Multidrug resistance in a small cell lung cancer line: rapid selection with etoposide and differential chemosensitization with cyclosporin A

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12 December 2020

Potentiation of 4'-(9-acridinylamino)methanesulphon-m-anisidine) action by verapamil

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12 December 2020

Cross-resistance of an amsacrine-resistant human leukemia line to topoisomerase II reactive DNA intercalating agents. Evidence for two topoisomerase II directed drug actions

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12 December 2020

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12 December 2020

Molecular cloning and identification of a point mutation in the topoisomerase II cDNA from an etoposide-resistant Chinese hamster ovary cell line.

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12 December 2020

ATP-dependent DNA topoisonmerase from D. melanogaster reversibly catenates duplex DNA rings

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12 December 2020

Charles F. Kettering Prize. P-glycoprotein and resistance to anticancer drugs

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12 December 2020

Identification of a point mutation in the topoisomerase II gene from a human leukemia cell line containing an amsacrine-resistant form of topoisomerase II

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12 December 2020

Eukaryotic topoisomerase II. Characterization of enzyme turnover

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12 December 2020

Stimulation of intracellular topoisomerase I activity by vasopressin and thrombin. Differential regulation by pertussis toxin

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12 December 2020

Two independent amsacrine-resistant human myeloid leukemia cell lines share an identical point mutation in the 170 kDa form of human topoisomerase II

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12 December 2020

Topoisomerase II: A specific marker for cell proliferation

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12 December 2020

Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance.

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12 December 2020

Resistance to inhibitors of DNA topoisomerases

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12 December 2020

Topoisomerase II-dependent and -independent mechanisms of etoposide resistance in Chinese hamster cell lines

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12 December 2020

Reduced permeability in CHO cells as a mechanism of resistance to colchicine

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12 December 2020

Mechanisms of resistance to drugs that inhibit DNA topoisomerases

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12 December 2020

P-glycoprotein expression and DNA topoisomerase I and II activity in benign tumors of the ovary and in malignant tumors of the ovary, before and after platinum/cyclophosphamide chemotherapy

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12 December 2020

Mechanisms of multidrug resistance in cancer treatment

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12 December 2020

Cell cycle stage dependent variations in drug-induced topoisomerase II mediated DNA cleavage and cytotoxicity

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12 December 2020

Factors contributing to adriamycin sensitivity in human xenograft tumors: the relationship between expression of the MDR1, GST-pi and topoisomerase II genes and tumor sensitivity to adriamycin

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12 December 2020

Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II beta isoform

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12 December 2020

Regulation of topoisomerase I and II activities by cyclic nucleotide- and phospholipid-dependent protein kinases. Effects of interactions between the two transduction pathways

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12 December 2020

Resistance mechanisms to topoisomerase poisons: the application of cell culture methods

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12 December 2020

Regulation of DNA Supercoiling in Escherichia coli

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12 December 2020

Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content

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12 December 2020

Decatenation of kinetoplast DNA by topoisomerases

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12 December 2020

Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells

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12 December 2020

Topoisomerase II activity involved in cleaving DNA into topological domains is altered in a multiple drug-resistant Chinese hamster ovary cell line

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12 December 2020

A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: a genetic system for determining the targets of topoisomerase II inhibitors

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12 December 2020

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes

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12 December 2020

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle

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12 December 2020

Identifiers

DOI

10.1007/BF00744662

1 reference

PubMed ID

7765323

Dimensions Publication ID

21 September 2017

0 references

1 reference

PubMed ID

7765323