Role of alterations in Ca(2+)-associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons (Q40546260)

21 September 2017

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title

Role of alterations in Ca(2+)-associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons (English)

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polycyclic aromatic hydrocarbons

21 September 2017

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Davila DR

1

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21 September 2017

Davis DP

2

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21 September 2017

Campbell K

3

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21 September 2017

Cambier JC

4

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21 September 2017

Zigmond LA

5

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21 September 2017

Burchiel SW

6

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21 September 2017

1 June 1995

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Journal of Toxicology and Environmental Health

21 September 2017

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21 September 2017

45

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21 September 2017

2

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21 September 2017

101-126

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7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracel

21 September 2017

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https://api.crossref.org/works/10.1080%2F15287399509531985

Signal transduction pathways involved in B-cell induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Molecular themes in oncogenesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Antigen receptors on T and B lymphocytes: parallels in organization and function

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Inhibition of lymphocyte activation in splenic and gut-associated lymphoid tissues following oral exposure of mice to 7,12-dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Alterations in mitogen-induced calcium mobilization and intracellular free calcium produced by 7,12-dimethylbenz(a)anthracene in the Jurkat human T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

DMBA-induced cytotoxicity in lymphoid and nonlymphoid organs of B6C3F1 mice: relation of cell death to target cell intracellular calcium and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

DMBA induces programmed cell death (apoptosis) in the A20.1 murine B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Molecular mechanisms of transmembrane signaling in B lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

The B-cell antigen receptor: structure and function of primary, secondary, tertiary and quaternary components

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Signal transduction by the B cell antigen receptor and its coreceptors

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Tyrosine phosphorylation of phospholipase C induced by membrane immunoglobulin in B lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Inhibition of calcium-dependent pathways of B-cell activation by DMBA

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Suppression of local gut-associated and splenic mitogen responsiveness of lymphoid cells following oral exposure of B6C3F1 mice to 7,12-dimethylbenz6a9anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Immunosuppression following 7,12-dimethylbenz[a]anthracene exposure in B6C3F1 mice--II. Altered cell-mediated immunity and tumor resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Structure and function of the B cell antigen receptor

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Natural host defence during oncogenesis. NK activity and dimethylbenzanthracene carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Chemical separation of helper cell function and delayed hypersensitivity responses

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

2,3,7,8-tetrachlorodibenzo-p-dioxin-induced changes in immunocompetence: possible mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Suppression of murine cytotoxic T-lymphocyte induction following exposure to 7,12-dimethylbenz[A]anthracene: dysfunction of antigen recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Signals and signs for lymphocyte responses

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Persistence of calcium elevation in the HPB-ALL human T cell line correlates with immunosuppressive properties of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Suppression of the in vitro humoral immune response of mouse splenocytes by 7,12-dimethylbenz[a]anthracene metabolites and inhibition of immunosuppression by alpha-naphthoflavone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Generation of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene by murine splenic macrophages

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Metabolism of benzo[a]pyrene by murine splenic cell types

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Evaluation of murine splenic cell type metabolism of benzo[a]pyrene and functionality in vitro following repeated in vivo exposure to benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Fc epsilon R1-mediated tyrosine phosphorylation of multiple proteins, including phospholipase C gamma 1 and the receptor beta gamma 2 complex, in RBL-2H3 rat basophilic leukemia cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Induction of immunotoxicity by polycyclic hydrocarbons: role of the Ah locus.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Molecular and cellular basis of chemically induced immunotoxicity

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Differential immunotoxic effects of the environmental chemical benzo[a]pyrene in young and aged mice

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Activation of (+-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to diolepoxides by human polymorphonuclear leukocytes or myeloperoxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Mechanism of action of alpha-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Mechanisms of chemical carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Do CD4 and CD8 control T-cell activation via a specific tyrosine protein kinase?

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Inhibition of IL-2 responsiveness following exposure to benzo(a)pyrene is due to alterations in accessory cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

P450 genes: structure, evolution, and regulation

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Immune modification due to chemical interference with transmembrane signalling: Application to polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

CD4, CD8 and the TCR-CD3 complex: a novel class of protein-tyrosine kinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Immunosuppression following exposure to 7,12-dimethylbenz[a]anthracene (DMBA) in Ah-responsive and Ah-nonresponsive mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Suppression of splenic lymphocyte function by 7,12-dimethylbenz[a]anthracene (DMBA) in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Functional and biochemical disposition of 7,12-dimethylbenz[a]anthracene in murine lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

The effects of epoxidized xenobiotics on mitogen responsiveness and antibody-producing ability of murine spleen cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Neutrophil-derived oxidants as mediators of chemical activation in bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57B1/6 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Immunosuppression following 7,12-dimethylbenz[a]anthracene exposure in B6C3F1 mice. I. Effects on humoral immunity and host resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Persistent suppression of humoral and cell-mediated immunity in mice following exposure to the polycyclic aromatic hydrocarbon 7,12-dimethylbenz[a]anthracene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Signal transduction by lymphocyte antigen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Immunosuppression by polycyclic aromatic hydrocarbons: a structure-activity relationship in B6C3F1 and DBA/2 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

Effects of 7,12-dimethylbenz[a]anthracene on the superantigen toxic shock syndrome toxin (TSST-1)-induced proliferation and antibody secretion by human lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1080%2F15287399509531985

Integration of the human lymphocyte into immunotoxicological investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15287399509531985

10.1080/15287399509531985

21 January 2018

Identifiers

DOI

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21 September 2017

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