The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors (Q40559475)

21 September 2017

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors (English)

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21 September 2017

Trevor N Stitt

1

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21 September 2017

Doreen Drujan

2

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21 September 2017

Brian A Clarke

3

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21 September 2017

Frank Panaro

4

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21 September 2017

Yekatarina Timofeyva

5

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21 September 2017

William O Kline

6

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21 September 2017

Michael Gonzalez

7

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21 September 2017

George D Yancopoulos

8

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21 September 2017

David J Glass

9

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21 September 2017

language of work or name

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1 May 2004

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21 September 2017

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21 September 2017

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21 September 2017

395-403

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21 September 2017

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Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats

21 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Identification of ubiquitin ligases required for skeletal muscle atrophy

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https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

The phosphoinositide 3-kinase pathway

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https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Forkhead transcription factors: key players in development and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Protein turnover measured in vivo and in vitro in muscles undergoing compensatory growth and subsequent denervation atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Glucocorticoids and muscle catabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Ras is involved in nerve-activity-dependent regulation of muscle genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

The many forks in FOXO's road

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2804%2900211-4

7 January 2021

10.1016/S1097-2765(04)00211-4

Identifiers

DOI

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21 September 2017

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