Transcription of the insulin gene: towards defining the glucose-sensitive cis-element and trans-acting factors (Q40569624)

21 September 2017

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title

Transcription of the insulin gene: towards defining the glucose-sensitive cis-element and trans-acting factors (English)

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21 September 2017

D Melloul

1

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PubMed ID

7821736

21 September 2017

E Cerasi

series ordinal

2

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21 September 2017

1 September 1994

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21 September 2017

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21 September 2017

37 Suppl 2

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21 September 2017

S3-10

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https://scigraph.springernature.com/pub.10.1007/bf00400820

21 September 2017

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cites work

Insulin and glucose transporter gene expression in obesity and diabetes

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Individual protein-binding domains of the insulin gene enhancer positively activate beta-cell-specific transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

The COUP transcription factor binds to an upstream promoter element of the rat insulin II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

A tissue-specific nuclear factor binds to multiple sites in the human insulin-gene enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Insulin enhancer binding protein has helix-loop-helix structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Effects of Gestational Age, Birth and Feeding on the Insulinogenic Response to Glucose and Tolbutamide by Fetal and Newborn Rat Pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Control of insulin gene expression by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00400820

Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1.

21 January 2018

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12 December 2020

Regulation of insulin gene transcription

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12 December 2020

Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

1 reference

12 December 2020

Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements

1 reference

12 December 2020

A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

1 reference

12 December 2020

Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene

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12 December 2020

Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells

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12 December 2020

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

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12 December 2020

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses

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12 December 2020

Structure and evolution of the insulin gene

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12 December 2020

Regulation of insulin gene expression by glucose and calcium in transfected primary islet cultures

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12 December 2020

Monolayer culture of adult rat pancreatic islets on extracellular matrix: long term maintenance of differentiated B-cell function

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12 December 2020

A cDNA from a mouse pancreatic beta cell encoding a putative transcription factor of the insulin gene

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12 December 2020

Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters

1 reference

12 December 2020

Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells

1 reference

12 December 2020

Positive and negative regulation of the human insulin gene by multiple trans-acting factors

1 reference

12 December 2020

Eukaryotic transcriptional regulatory proteins

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12 December 2020

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA

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12 December 2020

A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer

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12 December 2020

Cellular and molecular biology of the beta cell

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12 December 2020

Glucose stimulation of the proinsulin synthesis in isolated pancreatic islets without increasing amount of proinsulin mRNA

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12 December 2020

Effects of glucose on proinsulin messenger RNA in rats in vivo

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12 December 2020

Decreased Cyclic AMP and Insulin Response to Glucose in Isolated Islets of Neonatal Rats

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12 December 2020

Glucose induces insulin gene transcription in a murine pancreatic beta-cell line

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12 December 2020

Glucose regulates preproinsulin messenger RNA levels in a clonal cell line of simian virus 40-transformed B cells

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12 December 2020

Sequence-specific interactions of nuclear factors with the insulin gene enhancer.

1 reference

12 December 2020

Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

1 reference

12 December 2020

How eukaryotic transcriptional activators work

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12 December 2020

Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cells

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12 December 2020

Regulation of human insulin gene expression in transgenic mice

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12 December 2020

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12 December 2020

Insulin biosynthesis. I. On the mechanism of glucose stimulation.

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12 December 2020

Effect of 5'-flanking sequence deletions on expression of the human insulin gene in transgenic mice.

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12 December 2020

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain

1 reference

12 December 2020

Two proteins act as the IUF1 insulin gene enhancer binding factor

1 reference

12 December 2020

Regulation and specificity of glucose-stimulated insulin gene expression in human islets of Langerhans

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12 December 2020

Glucose and RNA Synthesis in Mammalian Islets of Langerhans

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12 December 2020

Insulin deficiency and insulin resistance in type 2 (non-insulin-dependent) diabetes: quantitative contributions of pancreatic and peripheral responses to glucose homeostasis.

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12 December 2020

The Effects of Fasting and Feeding on Preproinsulin Messenger RNA in Rats

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12 December 2020

Glucose sensing in pancreatic islet beta cells: the key role of glucokinase and the glycolytic intermediates

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12 December 2020

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

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12 December 2020

Glucose-regulated proinsulin processing in isolated islets from rat pancreas

1 reference

12 December 2020

Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00400820

1 reference

21 September 2017

1 reference

PubMed ID

7821736