Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors. (Q40570706)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15060164%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors (English)

1 reference

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26 December 2019

1 reference

1 reference

2

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26 December 2019

Benjamin Buehrer

series ordinal

3

1 reference

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26 December 2019

4

Eckardt Treuter

1 reference

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26 December 2019

author name string

Nina Heldring

series ordinal

1

1 reference

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26 December 2019

Jan-Ake Gustafsson

series ordinal

5

1 reference

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26 December 2019

language of work or name

English

0 references

publication date

1 April 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15060164%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

26 December 2019

published in

1 reference

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26 December 2019

volume

24

1 reference

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26 December 2019

issue

8

1 reference

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26 December 2019

page(s)

3445-3459

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15060164%20AND%20SRC:MED&resulttype=core&format=json

Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents

26 December 2019

cites work

1 reference

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Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions

22 September 2017

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Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97)

22 September 2017

1 reference

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Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor alpha

22 September 2017

1 reference

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Molecular determinants for the tissue specificity of SERMs

22 September 2017

1 reference

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A negative coregulator for the human ER

22 September 2017

1 reference

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Mechanisms of estrogen action

22 September 2017

1 reference

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Development of peptide antagonists that target estrogen receptor-cofactor interactions

22 September 2017

1 reference

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A structural biologist's view of the oestrogen receptor.

22 September 2017

1 reference

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Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring?

22 September 2017

1 reference

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

22 September 2017

1 reference

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Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.

22 September 2017

1 reference

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Tamoxifen-bound estrogen receptor (ER) strongly interacts with the nuclear matrix protein HET/SAF-B, a novel inhibitor of ER-mediated transactivation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta

22 September 2017

1 reference

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Peptide antagonists of the human estrogen receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Molecular basis of agonism and antagonism in the oestrogen receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter in human breast cancer cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions

25 September 2017

1 reference

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Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen.

17 June 2018

1 reference

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A dynamic structural model for estrogen receptor-alpha activation by ligands, emphasizing the role of interactions between distant A and E domains

17 June 2018

1 reference

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Biomedicine. Defining the "S" in SERMs

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Antagonists selective for estrogen receptor alpha

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381632

Identification of charged residues in an N-terminal portion of the hormone-binding domain of the human estrogen receptor important in transcriptional activity of the receptor

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15060164

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15060164

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.24.8.3445-3459.2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15060164%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15060164%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference