Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle (Q40579976)

21 September 2017

title

Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle (English)

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21 September 2017

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Joanne L Leaney

1

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21 September 2017

Amy Benians

2

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21 September 2017

Sean Brown

3

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21 September 2017

Muriel Nobles

4

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21 September 2017

David Kelly

5

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21 September 2017

Andrew Tinker

6

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21 September 2017

publication date

10 March 2004

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American Journal of Physiology - Cell Physiology

21 September 2017

published in

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21 September 2017

volume

287

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21 September 2017

issue

1

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21 September 2017

page(s)

C182-91

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Overexpression of monomeric and multimeric GIRK4 subunits in rat atrial myocytes removes fast desensitization and reduces inward rectification of muscarinic K(+) current (I(K(ACh))). Evidence for functional homomeric GIRK4 channels.

21 September 2017

cites work

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The dynamics of formation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor

21 January 2018

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Agonist unbinding from receptor dictates the nature of deactivation kinetics of G protein-gated K + channels

21 January 2018

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Desensitization of mu-opioid receptor-evoked potassium currents: initiation at the receptor, expression at the effector

21 January 2018

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G protein-independent inhibition of GIRK current by adenosine in rat atrial myocytes overexpressing A1 receptors after adenovirus-mediated gene transfer.

21 January 2018

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Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogue

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A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins

21 January 2018

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Acetylcholine-induced phosphatidylinositol 4,5-bisphosphate depletion does not cause short-term desensitization of G protein-gated inwardly rectifying K+ current in mouse atrial myocytes

21 January 2018

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Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels

21 January 2018

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Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers

21 January 2018

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Atrial G protein-activated K+ channel: expression cloning and molecular properties

21 January 2018

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RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels

21 January 2018

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The bee venom peptide tertiapin underlines the role of I(KACh) in acetylcholine-induced atrioventricular blocks

21 January 2018

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Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3

21 January 2018

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Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3.

21 January 2018

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Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization.

21 January 2018

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The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins

21 January 2018

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Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel

21 January 2018

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Acetylcholine activation of K+ channels in cell-free membrane of atrial cells

21 January 2018

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Short-term desensitization of muscarinic K+ channel current in isolated atrial myocytes and possible role of GTP-binding proteins

21 January 2018

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Contribution of Kir3.1, Kir3.2A and Kir3.2C subunits to native G protein‐gated inwardly rectifying potassium currents in cultured hippocampal neurons

21 January 2018

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Regulation of a G protein-gated inwardly rectifying K+ channel by a Ca(2+)-independent protein kinase C

21 January 2018

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The G protein alpha subunit has a key role in determining the specificity of coupling to, but not the activation of, G protein-gated inwardly rectifying K(+) channels

21 January 2018

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The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel

21 January 2018

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Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain

21 January 2018

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The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.

21 January 2018

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G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

21 January 2018

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Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes.

21 January 2018

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Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell

21 January 2018

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Twelfth Gaddum memorial lecture. Drug receptors and the inhibition of nerve cells

21 January 2018

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Characterization of synaptically elicited GABAB responses using patch-clamp recordings in rat hippocampal slices

21 January 2018

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GTP-binding proteins couple cardiac muscarinic receptors to a K channel.

21 January 2018

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Structure, function, and control of phosphoinositide-specific phospholipase C

21 January 2018

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Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits

21 January 2018

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Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

21 January 2018

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Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants.

21 January 2018

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Abnormal heart rate regulation in GIRK4 knockout mice.

21 January 2018

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10.1152/AJPCELL.00540.2003

21 January 2018

Identifiers

DOI

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21 September 2017

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