The role of tyrosine residues in the extracellular domain of the 5-hydroxytryptamine3 receptor. (Q40582728)

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24 November 2019

title

The role of tyrosine residues in the extracellular domain of the 5-hydroxytryptamine3 receptor (English)

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24 November 2019

1

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24 November 2019

2

Sarah C R Lummis

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24 November 2019

language of work or name

English

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publication date

3 March 2004

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Journal of Biological Chemistry

24 November 2019

published in

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24 November 2019

volume

279

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24 November 2019

issue

22

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24 November 2019

page(s)

23294-23301

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

24 November 2019

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Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits.

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The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review)

21 January 2018

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Ligands, Receptor Models, and Evolution

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Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques

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Prediction of 5-HT3 receptor agonist-binding residues using homology modeling.

21 January 2018

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Involvement of tryptophan residue(s) in the specific binding of agonists/antagonists to 5-HT3 receptors in NG108-15 clonal cells

21 January 2018

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Structural features of the ligand-binding domain of the serotonin 5HT3 receptor

21 January 2018

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Identification of critical residues in loop E in the 5-HT3ASR binding site

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Antibodies against the extracellular domain of the 5-HT3 receptor label both native and recombinant receptors

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High-efficiency transformation of mammalian cells by plasmid DNA

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.

21 January 2018

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Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

21 January 2018

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The role and predicted propensity of conserved proline residues in the 5-HT3 receptor.

21 January 2018

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The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain

21 January 2018

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Immunological characterization of 5-HT3 receptor transmembrane topology

21 January 2018

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The 4'lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors

21 January 2018

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Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily

21 January 2018

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Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

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Coupling of agonist binding to channel gating in the GABA(A) receptor

21 January 2018

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Protein oligomerization in the endoplasmic reticulum

21 January 2018

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Discovery of a protein sequence in the N-terminal region of the human neuronal alpha7 nicotinic acetylcholine receptor involved in homomeric interactions

21 January 2018

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Orientation of d-tubocurarine in the muscle nicotinic acetylcholine receptor-binding site

21 January 2018

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Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: antagonist footprint and secondary structure prediction

21 January 2018

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Identification of equivalent residues in the gamma, delta, and epsilon subunits of the nicotinic receptor that contribute to alpha-bungarotoxin binding

21 January 2018

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Identification of residues at the alpha and epsilon subunit interfaces mediating species selectivity of Waglerin-1 for nicotinic acetylcholine receptors

21 January 2018

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Structure of the agonist-binding sites of the Torpedo nicotinic acetylcholine receptor: affinity-labeling and mutational analyses identify gamma Tyr-111/delta Arg-113 as antagonist affinity determinants

21 January 2018

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Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor epsilon subunit

21 January 2018

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GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

21 January 2018

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Distinct agonist- and antagonist-binding sites on the glycine receptor

21 January 2018

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A mutational analysis of the acetylcholine receptor channel transmitter binding site

21 January 2018

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Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge?

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M314075200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14998995%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

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