Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1. (Q40597193)

21 September 2017

Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1. (English)

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21 September 2017

4

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M Brucet

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21 September 2017

L Marqués

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2

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C Sebastián

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A Celada

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1 January 2004

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21 September 2017

26-35

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https://scigraph.springernature.com/pub.10.1038/sj.gene.6364035

21 September 2017

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TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

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Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter

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A single-nucleotide deletion leads to rapid degradation of TAP-1 mRNA in a melanoma cell line.

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Defective function of the proteasome in autoimmunity: involvement of impaired NF-kappaB activation

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Synergistic induction of the Tap-1 gene by IFN-gamma and lipopolysaccharide in macrophages is regulated by STAT1.

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How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene

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Different requirements for signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 in the regulation of low molecular mass polypeptide 2 and transporter associated with antigen processing 1 gene expression.

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Interferon-gamma activates multiple pathways to regulate the expression of the genes for major histocompatibility class II I-A beta, tumor necrosis factor and complement component C3 in mouse macrophages

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression.

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Identification and characterization of a novel transcriptional silencer in the human collagen type IV gene COL4A2.

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Cooperation between complexes that regulate chromatin structure and transcription

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Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

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Cell biology of antigen processing and presentation to major histocompatibility complex class I molecule-restricted T lymphocytes

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7 January 2021

Interferon induction of TAP1: the phosphatase SHP-1 regulates crossover between the IFN-alpha/beta and the IFN-gamma signal-transduction pathways

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7 January 2021

Markedly decreased expression of TAP1 and LMP2 genes in HLA class I-deficient human tumor cell lines

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From transcription to cell surface expression, the induction of MHC class II I-Aα by interferon-γ in macrophages is regulated at different levels

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7 January 2021

Molecular basis for lack of expression of HLA class I antigens in human small-cell lung carcinoma cell lines

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7 January 2021

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

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7 January 2021

Identifiers

DOI

10.1038/SJ.GENE.6364035

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Dimensions Publication ID

21 September 2017

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