Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2. (Q40601385)

21 September 2017

Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2. (English)

1 reference

21 September 2017

Oleg Tikhomirov

1

1 reference

PubMed ID

14711810

21 September 2017

Graham Carpenter

series ordinal

2

1 reference

PubMed ID

14711810

21 September 2017

language of work or name

English

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publication date

7 January 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

13

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21 September 2017

12988-12996

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The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

21 September 2017

1 reference

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The ErbB receptor tyrosine family as signal integrators

21 January 2018

1 reference

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Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels

21 January 2018

1 reference

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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

21 January 2018

1 reference

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All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired

21 January 2018

1 reference

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Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation

21 January 2018

1 reference

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Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

21 January 2018

1 reference

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ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors.

21 January 2018

1 reference

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Untangling the ErbB signalling network

21 January 2018

1 reference

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The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

21 January 2018

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The EGF receptor family as targets for cancer therapy

21 January 2018

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Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

21 January 2018

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

21 January 2018

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The role of overexpressed HER2 in transformation

21 January 2018

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erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

21 January 2018

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EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival.

21 January 2018

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Prognostic value of the combination of epidermal growth factor receptor and c-erbB-2 in breast cancer

21 January 2018

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The EGF/ErbB receptor family and apoptosis

21 January 2018

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Modulation of cyclic AMP accumulation in GH3 cells by a phorbol ester and thyroliberin

21 January 2018

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The induction of apoptosis in human mammary luminal epithelial cells by expression of activated c-neu and its abrogation by glucocorticoids

21 January 2018

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Increased expression of c-erbB-2 in hormone-dependent breast cancer cells inhibits cell growth and induces differentiation.

21 January 2018

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Dominant negative knockout of p53 abolishes ErbB2-dependent apoptosis and permits growth acceleration in human breast cancer cells

21 January 2018

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Inhibition of mouse mammary ductal morphogenesis and down-regulation of the EGF receptor by epidermal growth factor

21 January 2018

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21 January 2018

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Ductal growth is impeded in mammary glands of C-neu transgenic mice.

21 January 2018

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Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera

21 January 2018

1 reference

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Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

21 January 2018

1 reference

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Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes

21 January 2018

1 reference

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

1 reference

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

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Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27

21 January 2018

1 reference

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SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis

21 January 2018

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Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

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Requirement of c-Jun N terminal kinase and P38 mitogen-activated protein kinase for anti-IgM-induced reduction in mitochondrial membrane potential in CH31 B lymphoma cells

21 January 2018

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p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

21 January 2018

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Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.

21 January 2018

1 reference

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Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells.

21 January 2018

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Regulation of mouse mammary gland development and tumorigenesis by the ERBB signaling network

21 January 2018

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Selective changes in EGF receptor expression and function during the proliferation, differentiation and apoptosis of mammary epithelial cells.

21 January 2018

1 reference

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Changes in ErbB2 (her-2/neu), ErbB3, and ErbB4 during growth, differentiation, and apoptosis of normal rat mammary epithelial cells

21 January 2018

1 reference

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Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

21 January 2018

1 reference

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Lysophosphatidic acid inhibits epidermal-growth-factor-induced Stat1 signaling in human epidermoid carcinoma A431 cells

21 January 2018

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Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M311655200

1 reference

21 September 2017

1 reference

PubMed ID

14711810